Excess lifetime risks* of lung disease other than cancer mortality (excluding pneumonia) and radiographic silicosis in white men from exposure to respirable crystalline silica dust (unlagged), comparing analyses with and without restriction on cumulative exposures
| Lung disease other than cancer† | Radiographic silicosis‡ | |||
|---|---|---|---|---|
| Concentration (mg/m3) | All | <10 mg/m3.y | All | <10 mg/m3.y |
| *Excess risk estimates are per 1000 workers and assume workers were exposed to a constant silica concentration for up to 45 years between the ages of 20 and 65. Annual risks are accumulated up to the age of 85. | ||||
| †Poisson regression models with external standardisation using United States rates for lung disease other than cancer excluding pneumonia. Power model when not restricting observation on cumulative exposure; linear relative rate model when restricting observation to cumulative exposure <10 mg/m3.y. | ||||
| ‡Poisson regression model using three age strata (0–39, 40–59, 60–85), and two calendar strata (1942–54, 1955–94). “Shape” model when not restricting observation on cumulative exposure; linear relative rate model when restricting observation to cumulative exposure <10 mg/m3.y. | ||||
| 0.001 | 1.3 | 1.1 | 6.2 | 1.6 |
| 0.005 | 6.4 | 5.6 | 17.0 | 7.8 |
| 0.010 | 12.0 | 11.0 | 26.0 | 16.0 |
| 0.020 | 23.0 | 22.0 | 39.0 | 31.0 |
| 0.030 | 33.0 | 33.0 | 50.0 | 46.0 |
| 0.040 | 42.0 | 43.0 | 59.0 | 60.0 |
| 0.050 | 50.0 | 54.0 | 68.0 | 75.0 |
| 0.060 | 58.0 | 64.0 | 76.0 | 89.0 |
| 0.070 | 65.0 | 74.0 | 83.0 | 100.0 |
| 0.080 | 72.0 | 83.0 | 90.0 | 120.0 |
| 0.090 | 79.0 | 93.0 | 96.0 | 130.0 |
| 0.100 | 86.0 | 100.0 | 100.0 | 140.0 |
| 0.200 | 140.0 | 190.0 | 150.0 | 260.0 |