Age and smoking adjusted estimates of the odds ratio (OR) and 95% confidence interval (95% CI) for the association between the severity of VWF and alternative measures of vibration dose in the total sample of vibration exposed workers (n=1557)
| Quintiles of vibration dose | |||||||
|---|---|---|---|---|---|---|---|
| Dose definition | 1st | 2nd | 3rd | 4th | 5th | LR test (χ2, 12 df†) | |
| Values apply at the time of the examination. The outcome is an ordinal variable scaled according to a score of finger blanching severity (score 0 = no blanching, score 1–8, score 9–20, score ≥21). The outcome was dichotomised taking account of the ordering by using cumulative probabilities (score ≥1, score ≥9, score ≥21). In the ordered logistic regression models, vibration dose was included as a quintile based design variable, assuming the lowest quintile as the reference category. The likelihood ratio (LR) test for the measures of vibration dose is shown. | |||||||
| *p<0.001,†df = degrees of freedom. | |||||||
| Σti (hours) (×102) | midpoint | 9 | 31 | 68 | 150 | 375 | |
| Score ≥1 | OR (95% CI) | 1.0 (–) | 2.2 (1.3 to 3.6) | 2.2 (1.3 to 3.6) | 4.6 (2.8 to 7.4) | 7.2 (4.4 to 11.9) | |
| Score ≥9 | 1.0 (–) | 7.7 (2.7 to 22.2) | 9.1 (3.2 to 26.0) | 17.1 (6.1 to 47.8) | 32.9 (11.7 to 92.1) | ||
| Score ≥21 | 1.0 (–) | 6.0 (1.4 to 25.9) | 6.1 (1.4 to 26.2) | 8.2 (2.0 to 34.3) | 24.1 (5.9 to 98.7) | 138.9* | |
| Σawiti (ms−2h) (×103) | midpoint | 6.5 | 23 | 50 | 127 | 415 | |
| Score ≥1 | OR (95% CI) | 1.0 (–) | 1.2 (0.8 to 2.0) | 2.0 (1.2 to 3.1) | 3.0 (1.9 to 4.7) | 6.5 (4.1 to 10.4) | |
| Score ≥9 | 1.0 (–) | 3.0 (1.4 to 6.5) | 3.5 (1.7 to 7.5) | 6.9 (3.4 to 14.3) | 15.0 (7.3 to 30.8) | ||
| Score ≥21 | 1.0 (–) | 4.1 (1.2 to 14.3) | 4.0 (1.1 to 13.9) | 5.8 (1.7 to 19.6) | 15.1 (4.6 to 49.2) | 139.5* | |
| Σawi2ti (m2s−4h) (×104) | midpoint | 4 | 14.5 | 42.5 | 183 | 735 | |
| Score ≥1 | OR (95% CI) | 1.0 (–) | 1.7 (1.1 to 2.8) | 2.3 (1.4 to 3.6) | 2.9 (1.8 to 4.5) | 4.9 (3.1 to 7.7) | |
| Score ≥9 | 1.0 (–) | 2.9 (1.5 to 5.7) | 3.7 (1.9 to 7.2) | 4.7 (2.5 to 9.1) | 9.1 (4.8 to 17.2) | ||
| Score ≥21 | 1.0 (–) | 2.5 (1.0 to 6.5) | 2.2 (0.8 to 5.7) | 3.2 (1.3 to 8.0) | 6.8 (2.8 to 16.6) | 86.4* | |
| Σawi4ti (m4s−8h) (×106) | midpoint | 1 | 6 | 71.5 | 661 | 3686 | |
| Score ≥1 | OR (95% CI) | 1.0 (–) | 1.9 (1.2 to 3.0) | 2.7 (1.8 to 4.3) | 2.6 (1.7 to 4.1) | 3.8 (2.5 to 5.8) | |
| Score ≥9 | 1.0 (–) | 2.4 (1.4 to 4.3) | 2.8 (1.6 to 4.9) | 3.3 (1.9 to 5.8) | 4.9 (2.8 to 8.3) | ||
| Score ≥21 | 1.0 (–) | 1.3 (0.6 to 2.8) | 1.2 (0.5 to 2.5) | 1.8 (0.9 to 3.9) | 2.9 (1.5 to 5.7) | 62.7* | |
| Σauwiti (ms−2h) (×104) | midpoint | 5.5 | 19 | 41.5 | 92.5 | 256 | |
| Score ≥1 | OR (95% CI) | 1.0 (–) | 1.4 (0.9 to 2.4) | 2.4 (1.5 to 4.0) | 3.4 (2.1 to 5.4) | 8.2 (5.0 to 13.4) | |
| Score ≥9 | 1.0 (–) | 3.0 (1.3 to 7.2) | 6.1 (2.7 to 13.9) | 7.7 (3.4 to 17.3) | 21.8 (9.8 to 48.7) | ||
| Score ≥21 | 1.0 (–) | 4.7 (1.0 to 21.5) | 8.4 (1.9 to 36.2) | 7.6 (1.8 to 32.6) | 24.3 (5.8 to 101) | 149.6* | |
| Σauwi2ti (m2s−4h) (×106) | midpoint | 3 | 11.5 | 27.5 | 75.5 | 249 | |
| Score ≥1 | OR (95% CI) | 1.0 (–) | 1.4 (0.8 to 2.2) | 2.0 (1.3 to 3.2) | 2.5 (1.6 to 4.0) | 6.4 (4.0 to 10.2) | |
| Score ≥9 | 1.0 (–) | 2.4 (1.2 to 4.9) | 3.1 (1.6 to 6.0) | 4.3 (2.3 to 8.3) | 10.6 (5.6 to 20.2) | ||
| Score ≥21 | 1.0 (–) | 1.7 (0.6 to 4.8) | 3.0 (1.2 to 7.7) | 2.3 (0.9 to 6.0) | 7.7 (3.2 to 18.8) | 121.3* | |
| Σauwi4ti (m4s−8h) (×1010) | midpoint | 1 | 4.5 | 18 | 77 | 274 | |
| Score ≥1 | OR (95% CI) | 1.0 (–) | 1.6 (1.0 to 2.5) | 1.3 (0.8 to 2.1) | 2.3 (1.5 to 3.5) | 4.6 (3.0 to 7.0) | |
| Score ≥9 | 1.0 (–) | 2.1 (1.2 to 3.7) | 1.6 (0.9 to 2.9) | 2.6 (1.5 to 4.5) | 5.7 (3.4 to 9.8) | ||
| Score ≥21 | 1.0 (–) | 1.7 (0.8 to 3.7) | 1.3 (0.5 to 3.0) | 1.8 (0.8 to 3.9) | 4.1 (2.0 to 8.5) | 84.1* | |