Age and smoking adjusted estimates of the odds ratio (OR) and 95% confidence interval (95% CI) for the association between VWF and alternative measures of vibration dose in the total sample of vibration exposed workers (n=1557)
Quintiles of vibration dose | ||||||||
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Dose definition | 1st | 2nd | 3rd | 4th | 5th | LR test (χ2, 4 df†) | H-L test (χ2, 8 df†) | |
In the logistic regression models, vibration dose was included as a quintile based design variable, assuming the lowest quintile as the reference category. The prevalence of VWF in each quintile of vibration dose is shown. The likelihood ratio (LR) test for the measures of vibration dose, and the Hosmer-Lemeshow (H-L) test for the goodness of fit of the logistic models are given. | ||||||||
Iaw = frequency-weighted acceleration; auw = unweighted acceleration; t = total operating time. | ||||||||
I*p<0.001,†df = degrees of freedom. | ||||||||
Σti (hours) (×102) | midpoint | 9 | 31 | 68 | 150 | 375 | ||
VWF (%) | 8.0 | 17.0 | 20.0 | 37.2 | 55.6 | 94.1* | 11.8 | |
OR (95% CI) | 1.0 (–) | 2.2 (1.3 to 3.6) | 2.2 (1.3 to 3.6) | 4.6 (2.8 to 7.6) | 7.2 (4.4 to 11.9) | (p=0.16) | ||
Σawiti (ms−2h) (×103) | midpoint | 6.5 | 23 | 50 | 127 | 415 | ||
VWF (%) | 10.0 | 15.1 | 22.5 | 33.0 | 58.2 | 106.2* | 4.3 | |
OR (95% CI) | 1.0 (–) | 1.2 (0.7 to 2.0) | 2.0 (1.2 to 3.1) | 2.9 (1.9 to 4.7) | 6.6 (4.1 to 10.5) | (p=0.83) | ||
Σawi2 ti (m2s−4h) (×104) | midpoint | 4 | 14.5 | 42.5 | 183 | 735 | ||
VWF (%) | 10.3 | 21.2 | 26.4 | 29.2 | 51.8 | 65.3* | 3.6 | |
OR (95% CI) | 1.0 (–) | 1.7 (1.1 to 2.8) | 2.3 (1.4 to 3.6) | 2.9 (1.8 to 4.5) | 5.0 (3.1 to 7.8) | (p=0.89) | ||
Σawi4ti (m4s−8h) (×106) | midpoint | 1 | 6 | 71.5 | 661 | 3686 | ||
VWF (%) | 11.9 | 26.4 | 29.3 | 26.3 | 45.0 | 46.5* | 6.8 | |
OR (95% CI) | 1.0 (–) | 1.9 (1.2 to 3.0) | 2.7 (1.8 to 4.3) | 2.6 (1.7 to 4.2) | 3.8 (2.5 to 5.9) | (p=0.56) | ||
Σauwiti (ms−2h) (×104) | midpoint | 5.5 | 19 | 41.5 | 92.5 | 256 | ||
VWF (%) | 8.7 | 14.4 | 23.2 | 32.4 | 60.1 | 115.1* | 4.4 | |
OR (95% CI) | 1.0 (–) | 1.4 (0.9 to 2.4) | 2.4 (1.5 to 3.9) | 3.4 (2.1 to 5.5) | 8.4 (5.1 to 13.8) | (p=0.78) | ||
Σauwi2 ti (m2s−4h) (×106) | midpoint | 3 | 11.5 | 27.5 | 75.5 | 249 | ||
VWF (%) | 10.3 | 16.8 | 23.3 | 29.4 | 59.0 | 100.2* | 5.6 | |
OR (95% CI) | 1.0 (–) | 1.4 (0.9 to 2.3) | 2.0 (1.2 to 3.2) | 2.6 (1.6 to 4.0) | 6.5 (4.1 to 10.3) | (p=0.69) | ||
Σauwi4ti (m4s−8h) (×1010) | midpoint | 1 | 4.5 | 18 | 77 | 274 | ||
VWF (%) | 12.9 | 24.6 | 18.0 | 27.2 | 56.0 | 72.8* | 7.9 | |
OR (95% CI) | 1.0 (–) | 1.6 (1.0 to 2.5) | 1.3 (0.8 to 2.1) | 2.3 (1.5 to 3.5) | 4.6 (3.0 to 7.1) | (p=0.44) |