Odds ratios (95% CI) for lung cancer among tin miners by cumulative dust exposure and duration of exposure*
| Three tin mines in Dachang | Limu tin mine | Total | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Cases | Controls | OR (95% CI) | Cases | Controls | OR (95% CI) | Cases | Controls | OR (95% CI) | |
| *Adjusted for tobacco smoking; †two sided p value. | |||||||||
| Cumulative total dust concentration (mg/m3-y): | |||||||||
| No exposure | 16 | 146 | 1.0 (—) | 2 | 19 | 1.0 (—) | 18 | 165 | 1.0 (—) |
| Low (<50) | 27 | 119 | 2.0 (1.0 to 4.0) | 6 | 26 | 2.1 (0.4–10.2) | 33 | 145 | 2.1 (1.1–3.8) |
| Medium (50–119.9) | 23 | 119 | 1.7 (0.8 to 3.5) | 8 | 44 | 1.5 (0.3 to 8.1) | 31 | 163 | 1.7 (0.9 to 3.1) |
| High (≥120) | 35 | 105 | 3.0 (1.6 to 5.8) | 13 | 49 | 2.4 (0.6 to 10.2) | 48 | 154 | 2.8 (1.6 to 5.0) |
| p Value for trend† | χ2=12.40 p=0.006 | χ2=1.65 p=0.649 | χ2=13.50 p=0.004 | ||||||
| Duration of exposure: | |||||||||
| No | 16 | 146 | 1.0 (—) | 2 | 19 | 1.0 (—) | 18 | 165 | 1.0 (—) |
| 0–9.9 | 28 | 133 | 1.8 (1.0 to 3.5) | 8 | 31 | 2.2 (0.4 to 11.3) | 36 | 164 | 1.9 (1.0 to 3.5) |
| 10–19.9 | 35 | 125 | 2.5 (1.3 to 4.1) | 11 | 55 | 1.9 (0.4 to 8.3) | 46 | 180 | 2.3 (1.3 to 4.1) |
| ≥20 | 22 | 85 | 2.3 (1.2 to 4.2) | 8 | 33 | 2.0 (0.4 to 9.4) | 30 | 118 | 2.3 (1.2 to 4.2) |
| p Value for trend† | χ2=9.44 p=0.024 | χ2=1.32 p=0.726 | χ2=9.63 p=0.022 | ||||||