Table 4

Incidence rate ratios for bladder cancer for occupational exposures (ever exposed v non-exposed (exp v non)) stratified upon cigarette smoking habit and cigarette smoking amount; Netherlands cohort study (1986–92)

Cigarette smokingPaint componentsPAH4-150Diesel exhaust
Cases
(exp v non)4-150
RR (95% CI)4-151Cases
(exp v non)4-150
RR (95% CI)4-151Cases
(exp v non)4-150
RR (95% CI)4-151
Never smoker4-153 2/341.35 (0.26 to 7.12)0/36Too few cases2/340.51 (0.11 to 2.35)
Smoking status
 Former4-160 13/2234-152 0.65 (0.34 to 1.26)15/2214-152 0.67 (0.36 to 1.27)46/1904-152 1.01 (0.68 to 1.49)
  <154-151 cigarettes/day4-164 5/641.13 (0.37 to 3.43)4/640.59 (0.19 to 1.79)7/610.38 (0.11 to 1.28)
  ⩾154-151 cigarettes/day4-164 8/1510.42 (0.17 to 1.03)11/1490.25 (0.00 to 4.28)38/1221.37 (0.74 to 2.56)
 Current4-160 32/2234-152 2.22 (1.15 to 4.29)24/2284-152 1.16 (0.60 to 2.23)50/2014-152 1.24 (0.81 to 1.90)
  <154-151 cigarettes/day4-164 9/651.40 (0.50 to 3.93)7/671.37 (0.25 to 7.44)15/570.99 (0.41 to 2.43)
  ⩾154-151 cigarettes/day4-164 20/1293.53 (1.52 to 8.22)16/1311.61 (0.62 to 4.17)29/1191.22 (0.63 to 2.39)
  • 4-150 Number of exposed and non-exposed bladder cancer cases included in the analysis.

  • 4-151 Adjusted for age and other occupational exposures.

  • 4-152 The numbers of exposed and non-exposed cases in the strata of cigarette smoking amount might not add up due to missing data on the number of cigarettes smoked per day.

  • 4-153 The reference category (RR=1.0) is formed by subjects not exposed to the corresponding occupational risk factor.

  • 4-160 Adjusted for age, other occupational exposures, cigarette smoking amount (cigarettes/day), and cigarette smoking duration (y).

  • 4-164 Adjusted for age, other occupational exposures, and cigarette smoking duration (y).

  • PAHs=polycyclic aromatic hydrocarbons.