Table 3

Urinary 1-OHP concentrations (μmol/mol creatinine) by polymorphism of metabolic enzymes in the controls and exposed workers

		Controls				Coke oven workers^3-151
		n	GM (25, 75 percentile)			p Value	n	GM (25, 75 percentile)	p Value
CYP1A1:
Ile/Ile	29	0.55 (0.30, 1.03)	0.86^3-152		76	9.91 (5.83, 20.23)	0.03^3-152
Ile/Val	14	0.63 (0.50, 0.80)			56	10.38 (5.08, 18.23)
Val/Val	4	0.63 (0.35, 1.45)			7	24.77 (10.63, 25.78)^3-160
GSTM1:
Present	18	0.71 (0.50, 1.20)	0.14		58	10.52 (5.00, 17.50)	0.91
Null	30	0.52 (0.30, 0.80)			82	10.67 (5.65, 22.30)
GSTT1:
Present	18	0.54 (0.30, 1.00)	0.54		61	10.07 (5.53, 20.35)	0.31
Null	30	0.62 (0.40, 0.90)			78	11.46 (6.45, 19.60)
GSTP1:
AA	31	0.54 (0.30, 0.95)	0.57^3-152		92	10.28 (5.53, 20.68)	0.62^3-152
AG	15	0.69 (0.50, 0.98)			41	11.32 (6.10, 19.20)
GG	2	0.58 (0.50, 0.70)			6	8.47 (4.10, 13.10)

↵3-160 p<0.01 v Ile/Ile type; p=0.01vIle/Val type.
↵3-151 Data were adjusted for levels of exposure.
↵3-152 ANOVA.
GM=geometric mean.