Table 5

Bronchial responsiveness in historical controls (HC) and in the study group stratified by exposure to wood dust expressed in terms of the cumulative dust exposure index

VariableHCExposure (y.mg/m3)p Value5-150p Value5-151
0⩽7070–110110–160<160
n2001328282533
MBC+ n (%)20  (10)1  (8)4  (14.3)6  (21.4)6  (21.4)9  (27.3)0.775-152 0.0025-152
DRS  (mean (SD))0.28 (0.08)0.31 (0.08)0.27 (0.07)0.25 (0.08)0.25 (0.09)0.24 (0.1)0.045-153 0.0145-153
  • 5-150 HC excluded from the analysis.

  • 5-151 HC included in the analysis.

  • 5-152 Logistic regression after adjustment for baseline FEV1and age.

  • 5-153 Linear regression after adjustment for FEV1 and age.

  • MBC+=decline in FEV1 by ⩾20%; DRS=1/(% decline in FEV1/μmol +2.5).