Table 3

Estimates of odds ratios (ORs) (95% CIs) and mutliplicative effects (×) for cumulative exposure variables adjusted for important covariates

Exposure Symptoms3-151(OR) Hot QST3-152 (× effect) Cold QST3-152 (× effect) Vibration QST3-152 (× effect)
Unadjusted for covariates:
 DAYS 3-1501.15  (1.04  to  1.26)0.99  (0.93  to  1.05) 3-150 1.04  (1.00  to 1.09) 3-1501.06  (1.01  to  1.12)
 OPEXP 3-1501.13 (1.03 to  1.24)1.01 (0.95 to  1.07) 3-1501.04 (1.01 to  1.09) 3-1501.06 (1.01 to  1.12)
Adjusted for covariates:
 DAYS 3-1501.13 (1.01 to  1.25) 3-1500.94 (0.89 to  1.00)0.99 (0.95 to  1.03)1.01 (0.96 to  1.06)
 OPEXP 3-1501.11 (1.01 to  1.23)0.96 (0.91 to  1.01)0.99 (0.96 to  1.03)1.01 (0.96 to  1.05)
Adjusted for covariates excluding high leverage points:3-153
 DAYS1.07 (0.92 to  1.24) 3-1500.92 (0.86 to  0.99)0.98 (0.94 to  1.03)1.03 (0.97 to  1.09)
 OPEXP1.06 (0.91 to  1.24) 3-1500.93 (0.86 to  1.00)0.98 (0.93 to  1.03)1.04 (0.97 to  1.10)
  • 3-150 p<0.05.

  • 3-151 Adjusted for age, country, and occupational group.

  • 3-152 Adjusted for age, sex, country, and occupational group.

  • 3-153 Omitting 4, 17, 10, and 18 data points for symptoms, hot, cold, and vibration QSTs respectively.

  • Variables DAYS and OPEXP represent cumulative exposure indices for exposure to OPs and days dipped, scaled by the interquartile range of the values across all subjects: 74 days for DAYS; and 2350 nmol.mmol−1.days for OPEXP.