Geometric mean (SE) concentrations of urinary 8-OH-dG (ng/mg creatinine) in firefighters by genetic subtypes
| Subjects (n) | No active duty (n=24) | Less active duty (n=36) | More active duty (n=13) | |
| CYP1A1 MspI: | ||||
| m1/m1 | 23 | 13.2 (1.1) | 13.1 (1.2) | 14.3 (1.3) |
| m1/m2,m2/m2 | 50 | 11.8 (1.1) | 11.9 (1.1) | 14.1 (1.1) |
| CYP1A1 ile-val: | ||||
| ile/ile | 41 | 12.5 (1.1) | 13.1 (1.1) | 16.0 (1.2) |
| ile/val, val/val | 32 | 11.9 (1.1) | 11.4 (1.1) | 12.7 (1.1) |
| CYP2E1: | ||||
| c1/c1 | 44 | 11.5 (1.1) | 11.7 (1.1) | 13.6 (1.1) |
| c1/c2,c2/c2 | 29 | 13.9 (1.1) | 13.4 (1.2) | 14.6 (1.1) |
| GSTM1: | ||||
| + | 37 | 12.5 (1.1) | 12.4 (1.1) | 13.6 (1.1) |
| − | 36 | 12.0 (1.1) | 12.2 (1.2) | 14.4 (1.1) |
| GSTT1: | ||||
| + | 39 | 12.2 (1.1) | 12.2 (1.1) | 15.1 (1.1) |
| − | 34 | 12.4 (1.1) | 12.4 (1.1) | 12.2 (1.1) |