Serious errors and omissions occurring in papers submitted to OEM
Design: |
Authors unclear of type of epidemiological study |
Adequacy of sample size not considered |
Bias in selection of subjects |
Execution: |
Data collection problems and missing data not adequately reported |
Non-respondents not investigated |
Sample selection and exclusions inadequately justified |
Analysis: |
Parametric tests carried out on obviously skewed data |
Use of multiple paired tests |
Inappropriate analysis of repeated measures or longitudinal data |
Incorrect analysis of matched case-control studies |
Modelling incorrect—for example, inadequate adjustment for confounders, interaction terms not included, only significant variables from preliminary analyses included |
Presentation: |
Inadequate description of the methodology and statistical procedures |
Inappropriate summary statistics for non-normal data |
No presentation of risk estimates—for example, odds ratios—and confidence intervals |
Interpretation: |
Potential bias due to sample selection, no or poor response, missing values, exclusions |
Lack of statistical power not considered |
No allowance made for multiple testing |
Misunderstanding and misinterpretation of results from models |