Table 4

Crude and adjusted hazards ratios (HRs) (95% CIs) for predictors of all known angiosarcomas (n=48)

VariablenPerson-yearsDeathsMortality / 100000CrudeAdjusted4-150
HR (95% CI)p Value4-151HR (95% CI)p Value4-151
Age at first exposure (y):0.330.52
 <2536191180811512.70ReferenceReference
 25–3441731362432216.151.3  (0.7  to  2.5)1.2  (0.6  to  2.3)
 ⩾352317622211117.681.8 (0.8 to  4.0)1.6 (0.7 to  3.5)
Duration of exposure (y):<0.0001<0.001
 <5477413620032.20ReferenceReference
 5–923837180668.363.7 (0.9 to  15.0)3.7 (0.9 to  14.7)
 10–191992690152637.6714.7 (4.4 to  48.8)15.9 (4.6 to  54.8)
 ⩾20960395241332.8911.0 (3.1 to  38.9)9.7 (2.6 to  36.4)
Year of first exposure:0.040.21
 <19502425926452526.98ReferenceReference
 1950–592806987291616.210.7 (0.3 to  1.3)0.5 (0.3 to  1.1)
 1960–72487812517175.590.3 (0.1 to  0.8)0.8 (0.3 to  2.1)
  • 4-150 Adjusted for age at first exposure, duration of exposure, and year of first exposure.

  • 4-151 Likelihood ratio test for equality of survivor functions controlling for time at risk.