RT Journal Article SR Electronic T1 Seroprevalence of the SARS-CoV-2 antibody in healthcare workers: a multicentre cross-sectional study in 10 Colombian cities JF Occupational and Environmental Medicine JO Occup Environ Med FD BMJ Publishing Group Ltd SP oemed-2021-107487 DO 10.1136/oemed-2021-107487 A1 Jeadran Nevardo Malagón-Rojas A1 Marcela Mercado-Reyes A1 Yezith G Toloza-Pérez A1 Eliana L Parra Barrera A1 Marien Palma A1 Esperanza Muñoz A1 Ronald López A1 Julia Almentero A1 Vivian V Rubio A1 Edgar Ibáñez A1 Eliana Téllez A1 Lucy G Delgado-Murcia A1 Claudia P Jimenez A1 Diego Viasus-Pérez A1 Marisol Galindo A1 Luisa Lagos A1 , YR 2021 UL http://oem.bmj.com/content/early/2021/12/05/oemed-2021-107487.abstract AB Background Healthcare workers are at increased risk of infection due to occupational exposure to SARS-CoV-2-infected patients. The objective of this study was to determine the seroprevalence of SARS-CoV-2 in healthcare workers in Colombia.Methods This study is a cross-sectional study focused on estimating the seroprevalence of SARS-CoV-2 antibodies in healthcare workers from 65 hospitals in 10 cities in Colombia during the second semester of 2020. The seroprevalence was determined using an automated immunoassay (Abbott SARS-CoV-2 CLIA IgG). The study included a survey to establish the sociodemographic variables and the risk of infection. A multivariate model was used to evaluate the association between the results of seroprevalence and risk factors.Results The global seroprevalence of antibodies against SARS-CoV-2 was 35% (95% Bayesian CI 33% to 37%). All the personnel reported the use of protective equipment. General services personnel and nurses presented the highest ratios of seroprevalence among the healthcare workers. Low socioeconomic strata have shown a strong association with seropositivity.Conclusion This study estimates the prevalence of SARS-CoV-2 infection among healthcare workers. Even though all the personnel reported the use of protective equipment, the seroprevalence in the general services personnel and nurses was high. Also, a significant difference by cities was observed.Data are available upon reasonable request. Data may be obtained from a third party and are not publicly available.