RT Journal Article
SR Electronic
T1 S-301 Sensing and sampling for the external exposome in occupational studies
JF Occupational and Environmental Medicine
JO Occup Environ Med
FD BMJ Publishing Group Ltd
SP A157
OP A157
DO 10.1136/OEM-2021-EPI.431
VO 78
IS Suppl 1
A1 Loh, Miranda
A1 Kuijpers, Eelco
A1 Ruiter, Sander
A1 Steinle, Susanne
A1 Mink, Jan
A1 Holgenelst, Koen
A1 Tromp, Peter
A1 Jagers, Ferry
A1 Cherrie, Mark
A1 Schlünssen, Vivi
A1 Lund Würtz, Anne Mette
A1 Kogevinas, Manolis
A1 Harding, Barbara
A1 Castaño Vinyals, Gemma
A1 Pronk, Anjoeka
YR 2021
UL http://oem.bmj.com/content/78/Suppl_1/A157.3.abstract
AB Introduction Characterizing the external exposome requires a combination of different measurement methods for multiple exposures.Objectives We describe the development of an external exposome assessment system for the EPHOR study, which focuses on cohorts for assessing working life exposures, particularly one case study on shift work and one on respiratory health. The system will be implemented in a weeklong intensive nested study.Methods A system of measurement using low-cost sensors, passive sampling methods, and a mobile phone app was developed and trialed. The low-cost sensor measures light, UV, noise, particulate matter, temperature and humidity in a high temporal resolution. Additionally, separate activity and heart rate monitors are added to the data stream. Passive sampling is used for a wide spectrum of chemical and biological agents. The phone app is used for asking a set of questions related to health and exposure factors on a daily basis. The low-cost sensor performance was compared to reference monitors in both a controlled laboratory setting (static) and in a free living setting (personal).Results Initial tests of the low-cost sensor system indicates that correlations with reference monitors are high for controlled laboratory tests but more variable when used in personal monitoring. Additional calibration may be necessary throughout the project, especially for particulate matter, with the possibility of using the raw sensor data (particle numbers of various sizes) calculating mass concentration.Conclusion A comprehensive protocol to measure the external exposome has been developed. Next steps include the development of external exposome profiles based on the collected data for use in exposure response analysis for various outcomes. It can be challenging to develop a one-size-fits-all external exposome system for exposome studies with different objectives. A flexible platform that can incorporate different sensors or measurement methods is an important feature of external exposome measurement systems.