RT Journal Article SR Electronic T1 Psychosocial impact of the COVID-19 pandemic on 4378 UK healthcare workers and ancillary staff: initial baseline data from a cohort study collected during the first wave of the pandemic JF Occupational and Environmental Medicine JO Occup Environ Med FD BMJ Publishing Group Ltd SP 801 OP 808 DO 10.1136/oemed-2020-107276 VO 78 IS 11 A1 Lamb, Danielle A1 Gnanapragasam, Sam A1 Greenberg, Neil A1 Bhundia, Rupa A1 Carr, Ewan A1 Hotopf, Matthew A1 Razavi, Reza A1 Raine, Rosalind A1 Cross, Sean A1 Dewar, Amy A1 Docherty, Mary A1 Dorrington, Sarah A1 Hatch, Stephani A1 Wilson-Jones, Charlotte A1 Leightley, Daniel A1 Madan, Ira A1 Marlow, Sally A1 McMullen, Isabel A1 Rafferty, Anne-Marie A1 Parsons, Martin A1 Polling, Catherine A1 Serfioti, Danai A1 Gaunt, Helen A1 Aitken, Peter A1 Morris-Bone, Joanna A1 Simela, Chloe A1 French, Veronica A1 Harris, Rachel A1 Stevelink, Sharon A M A1 Wessely, Simon YR 2021 UL http://oem.bmj.com/content/78/11/801.abstract AB Objectives This study reports preliminary findings on the prevalence of, and factors associated with, mental health and well-being outcomes of healthcare workers during the early months (April–June) of the COVID-19 pandemic in the UK.Methods Preliminary cross-sectional data were analysed from a cohort study (n=4378). Clinical and non-clinical staff of three London-based NHS Trusts, including acute and mental health Trusts, took part in an online baseline survey. The primary outcome measure used is the presence of probable common mental disorders (CMDs), measured by the General Health Questionnaire. Secondary outcomes are probable anxiety (seven-item Generalised Anxiety Disorder), depression (nine-item Patient Health Questionnaire), post-traumatic stress disorder (PTSD) (six-item Post-Traumatic Stress Disorder checklist), suicidal ideation (Clinical Interview Schedule) and alcohol use (Alcohol Use Disorder Identification Test). Moral injury is measured using the Moray Injury Event Scale.Results Analyses showed substantial levels of probable CMDs (58.9%, 95% CI 58.1 to 60.8) and of PTSD (30.2%, 95% CI 28.1 to 32.5) with lower levels of depression (27.3%, 95% CI 25.3 to 29.4), anxiety (23.2%, 95% CI 21.3 to 25.3) and alcohol misuse (10.5%, 95% CI 9.2 to 11.9). Women, younger staff and nurses tended to have poorer outcomes than other staff, except for alcohol misuse. Higher reported exposure to moral injury (distress resulting from violation of one’s moral code) was strongly associated with increased levels of probable CMDs, anxiety, depression, PTSD symptoms and alcohol misuse.Conclusions Our findings suggest that mental health support for healthcare workers should consider those demographics and occupations at highest risk. Rigorous longitudinal data are needed in order to respond to the potential long-term mental health impacts of the pandemic.Data are available on reasonable request. Data may be available on request to the corresponding author.