RT Journal Article SR Electronic T1 High physical work demands have worse consequences for older workers: prospective study of long-term sickness absence among 69 117 employees JF Occupational and Environmental Medicine JO Occup Environ Med FD BMJ Publishing Group Ltd SP 829 OP 834 DO 10.1136/oemed-2020-107281 VO 78 IS 11 A1 Lars Louis Andersen A1 Jacob Pedersen A1 Emil Sundstrup A1 Sannie Vester Thorsen A1 Reiner Rugulies YR 2021 UL http://oem.bmj.com/content/78/11/829.abstract AB Objective This study investigates the role of age for the prospective association between physical work demands and long-term sickness absence (LTSA).Methods We followed 69 117 employees of the general working population (Work Environment and Health in Denmark study 2012–2018), without LTSA during the past 52 weeks preceding initial interview, for up to 2 years in the Danish Register for Evaluation of Marginalisation. Self-reported physical work demands were based on a combined ergonomic index including seven different types of exposure during the working day. Using weighted Cox regression analyses controlling for years of age, gender, survey year, education, lifestyle, depressive symptoms and psychosocial work factors, we determined the interaction of age with physical work demands for the risk of LTSA.Results During follow-up, 8.4% of the participants developed LTSA. Age and physical work demands interacted (p<0.01). In the fully adjusted model, very high physical work demands were associated with LTSA with HRs of 1.18 (95% CI 0.93 to 1.50), 1.57 (95% CI 1.41 to 1.75) and 2.09 (95% CI 1.81 to 2.41) for 20, 40 and 60 years old (point estimates), respectively. Results remained robust in subgroup analyses including only skilled and unskilled workers and stratified for gender.Conclusion The health consequences of high physical work demands increase with age. Workplaces should consider adapting physical work demands to the capacity of workers in different age groups.The authors encourage collaboration and use of the data by other researchers. Data are stored on the secure server of Statistics Denmark, and researchers interested in using the data for scientific purposes should contact the authors.