RT Journal Article SR Electronic T1 Identification of early-stage silicosis through health screening of stone benchtop industry workers in Victoria, Australia JF Occupational and Environmental Medicine JO Occup Environ Med FD BMJ Publishing Group Ltd SP 296 OP 302 DO 10.1136/oemed-2020-106897 VO 78 IS 4 A1 Hoy, Ryan F A1 Glass, Deborah C A1 Dimitriadis, Christina A1 Hansen, Jessy A1 Hore-Lacy, Fiona A1 Sim, Malcolm R YR 2021 UL http://oem.bmj.com/content/78/4/296.abstract AB Objectives The popularity of high silica content artificial stone has been associated with emergence of severe, progressive silicosis as a major health issue affecting workers in the stone benchtop industry. This population-based health assessment programme has been implemented with the aim of identifcation of silica-associated disease at a preclinical stage.Methods All current and former workers from the stone benchtop industry in the State of Victoria are offered free health assessments. Primary evaluations include a standardised questionnaire, physical examination, spirometry and gas transfer assessment and International Labour Organisation-categorised chest X-ray. Secondary evaluations include high-resolution CT chest, blood tests and a respiratory physician evaluation.Results At the end of the first 12 months, 86/239 (36%) workers who had completed secondary evaluation were diagnosed with silicosis (65 simple silicosis and 21 complicated silicosis). 22 had worked in the industry for less than 10 years at the time of diagnosis. Of those with simple silicosis, 80% of workers reported breathlessness only with strenuous exercise (modified Medical Research Council score of 0), and lung function was well preserved (prebronchodilator forced vital capacity mean 99.8% predicted (SD 13.6), diffusion capacity of the lung for carbon monoxide mean 96.2% predicted (SD 18.0)). Antinuclear antibodies were detected in 37% with silicosis and 24% without silicosis.Conclusion Early results from this comprehensive health assessment programme have indicated a high proportion of referred artificial stone benchtop workers have silicosis, including many with early-stage disease. The common finding of antinuclear antibodies suggest significant potential for autoimmune disease in this occupational group.