RT Journal Article SR Electronic T1 Lung cancer risk in painters: results from the SYNERGY pooled case–control study consortium JF Occupational and Environmental Medicine JO Occup Environ Med FD BMJ Publishing Group Ltd SP 269 OP 278 DO 10.1136/oemed-2020-106770 VO 78 IS 4 A1 Neela Guha A1 Liacine Bouaoun A1 Hans Kromhout A1 Roel Vermeulen A1 Thomas Brüning A1 Thomas Behrens A1 Susan Peters A1 Véronique Luzon A1 Jack Siemiatycki A1 Mengting Xu A1 Benjamin Kendzia A1 Pascal Guenel A1 Danièle Luce A1 Stefan Karrasch A1 Heinz-Erich Wichmann A1 Dario Consonni A1 Maria Teresa Landi A1 Neil E Caporaso A1 Per Gustavsson A1 Nils Plato A1 Franco Merletti A1 Dario Mirabelli A1 Lorenzo Richiardi A1 Karl-Heinz Jöckel A1 Wolfgang Ahrens A1 Hermann Pohlabeln A1 Lap Ah TSE A1 Ignatius Tak-Sun Yu A1 Adonina Tardón A1 Paolo Boffetta A1 David Zaridze A1 Andrea 't Mannetje A1 Neil Pearce A1 Michael P A Davies A1 Jolanta Lissowska A1 Beata Świątkowska A1 John McLaughlin A1 Paul A Demers A1 Vladimir Bencko A1 Lenka Foretova A1 Vladimir Janout A1 Tamás Pándics A1 Eleonora Fabianova A1 Dana Mates A1 Francesco Forastiere A1 Bas Bueno-de-Mesquita A1 Joachim Schüz A1 Kurt Straif A1 Ann Olsson YR 2021 UL http://oem.bmj.com/content/78/4/269.abstract AB Objectives We evaluated the risk of lung cancer associated with ever working as a painter, duration of employment and type of painter by histological subtype as well as joint effects with smoking, within the SYNERGY project.Methods Data were pooled from 16 participating case–control studies conducted internationally. Detailed individual occupational and smoking histories were available for 19 369 lung cancer cases (684 ever employed as painters) and 23 674 age-matched and sex-matched controls (532 painters). Multivariable unconditional logistic regression models were adjusted for age, sex, centre, cigarette pack-years, time-since-smoking cessation and lifetime work in other jobs that entailed exposure to lung carcinogens.Results Ever having worked as a painter was associated with an increased risk of lung cancer in men (OR 1.30; 95% CI 1.13 to 1.50). The association was strongest for construction and repair painters and the risk was elevated for all histological subtypes, although more evident for small cell and squamous cell lung cancer than for adenocarcinoma and large cell carcinoma. There was evidence of interaction on the additive scale between smoking and employment as a painter (relative excess risk due to interaction >0).Conclusions Our results by type/industry of painter may aid future identification of causative agents or exposure scenarios to develop evidence-based practices for reducing harmful exposures in painters.