TY - JOUR T1 - Parental occupational exposure to low-frequency magnetic fields and risk of leukaemia in the offspring: findings from the Childhood Leukaemia International Consortium (CLIC) JF - Occupational and Environmental Medicine JO - Occup Environ Med SP - 746 LP - 753 DO - 10.1136/oemed-2019-105706 VL - 76 IS - 10 AU - Madar Talibov AU - Ann Olsson AU - Helen Bailey AU - Friederike Erdmann AU - Catherine Metayer AU - Corrado Magnani AU - Eleni Petridou AU - Anssi Auvinen AU - Logan Spector AU - Jacqueline Clavel AU - Eve Roman AU - John Dockerty AU - Atte Nikkilä AU - Olli Lohi AU - Alice Kang AU - Theodora Psaltopoulou AU - Lucia Miligi AU - Javier Vila AU - Elisabeth Cardis AU - Joachim Schüz Y1 - 2019/10/01 UR - http://oem.bmj.com/content/76/10/746.abstract N2 - Objectives Previously published studies on parental occupational exposure to extremely low-frequency magnetic fields (ELF-MF) and risk of acute lymphoblastic leukaemia (ALL) and acute myeloid leukaemia (AML) in their offspring were inconsistent. We therefore evaluated this question within the Childhood Leukemia International Consortium.Methods We pooled 11 case–control studies including 9723 childhood leukaemia cases and 17 099 controls. Parental occupational ELF-MF exposure was estimated by linking jobs to an ELF-MF job-exposure matrix (JEM). Logistic regression models were used to estimate ORs and 95% CIs in pooled analyses and meta-analyses.Results ORs from pooled analyses for paternal ELF-MF exposure >0.2 microtesla (µT) at conception were 1.04 (95% CI 0.95 to 1.13) for ALL and 1.06 (95% CI 0.87 to 1.29) for AML, compared with ≤0.2 µT. Corresponding ORs for maternal ELF-MF exposure during pregnancy were 1.00 (95% CI 0.89 to 1.12) for ALL and 0.85 (95% CI 0.61 to 1.16) for AML. No trends of increasing ORs with increasing exposure level were evident. Furthermore, no associations were observed in the meta-analyses.Conclusions In this large international dataset applying a comprehensive quantitative JEM, we did not find any associations between parental occupational ELF-MF exposure and childhood leukaemia. ER -