PT - JOURNAL ARTICLE AU - Hammer, Paula Edeusa Cristina AU - Garde, Anne Helene AU - Begtrup, Luise Moelenberg AU - Flachs, Esben Meulengracht AU - Hansen, Johnni AU - Hansen, Åse Marie AU - Hougaard, Karin Sørig AU - Kolstad, Henrik A AU - Larsen, Ann Dyreborg AU - Pinborg, Anja Bisgaard AU - Specht, Ina Olmer AU - Bonde, Jens Peter TI - Night work and sick leave during pregnancy: a national register-based within-worker cohort study AID - 10.1136/oemed-2018-105331 DP - 2019 Mar 01 TA - Occupational and Environmental Medicine PG - 163--168 VI - 76 IP - 3 4099 - http://oem.bmj.com/content/76/3/163.short 4100 - http://oem.bmj.com/content/76/3/163.full SO - Occup Environ Med2019 Mar 01; 76 AB - Objective The aim of our study was to investigate the acute effect of night work during pregnancy on the risk of calling in sick the following day using register-based information and the workers as their own controls.Methods Using the payroll-based national Danish Working Hour Database, including all public hospital employees in Denmark, we identified 9799 pregnant women with ≥1 day shift and ≥1 night shift and ≥1 day of sick leave during the first 32 pregnancy weeks from January 2007 to December 2013. We performed fixed effects logistic regression, that is, within-worker comparisons, of the risk of sick leave of any duration starting within 24 hours after night shifts of different length versus day shifts.Results Most of the participants were nurses (64%) or physicians (16%). We found an increased relative risk of sick leave following night shifts compared with day shifts during all pregnancy trimesters. The risk was highest for night shifts lasting >12 hours (OR 1.37, 95% CI 1.15 to 1.63 for nurses; OR 1.87, 95% CI 1.69 to 2.08 for physicians) and among women aged >35 years (OR 1.42, 95% CI 1.24 to 1.63).Conclusion Among Danish public hospital employees night shifts during pregnancy, especially shifts longer than 12 hours, increased the risk of calling in sick the following day independent of personal factors and time-invariant confounders in all pregnancy trimesters.