PT - JOURNAL ARTICLE AU - Chimed-Ochir Odgerel AU - Ken Takahashi AU - Tom Sorahan AU - Tim Driscoll AU - Christina Fitzmaurice AU - Makoto Yoko-o AU - Kittisak Sawanyawisuth AU - Sugio Furuya AU - Fumihiro Tanaka AU - Seichi Horie AU - Nico van Zandwijk AU - Jukka Takala TI - Estimation of the global burden of mesothelioma deaths from incomplete national mortality data AID - 10.1136/oemed-2017-104298 DP - 2017 Dec 01 TA - Occupational and Environmental Medicine PG - 851--858 VI - 74 IP - 12 4099 - http://oem.bmj.com/content/74/12/851.short 4100 - http://oem.bmj.com/content/74/12/851.full SO - Occup Environ Med2017 Dec 01; 74 AB - Background Mesothelioma is increasingly recognised as a global health issue and the assessment of its global burden is warranted.Objectives To descriptively analyse national mortality data and to use reported and estimated data to calculate the global burden of mesothelioma deaths.Methods For the study period of 1994 to 2014, we grouped 230 countries into 59 countries with quality mesothelioma mortality data suitable to be used for reference rates, 45 countries with poor quality data and 126 countries with no data, based on the availability of data in the WHO Mortality Database. To estimate global deaths, we extrapolated the gender-specific and age-specific mortality rates of the countries with quality data to all other countries.Results The global numbers and rates of mesothelioma deaths have increased over time. The 59 countries with quality data recorded 15 011 mesothelioma deaths per year over the 3 most recent years with available data (equivalent to 9.9 deaths per million per year). From these reference data, we extrapolated the global mesothelioma deaths to be 38 400 per year, based on extrapolations for asbestos use.Conclusions Although the validity of our extrapolation method depends on the adequate identification of quality mesothelioma data and appropriate adjustment for other variables, our estimates can be updated, refined and verified because they are based on commonly accessible data and are derived using a straightforward algorithm. Our estimates are within the range of previously reported values but higher than the most recently reported values.