RT Journal Article SR Electronic T1 Mortality from cancer and other causes among Italian chrysotile asbestos miners JF Occupational and Environmental Medicine JO Occup Environ Med FD BMJ Publishing Group Ltd SP 558 OP 563 DO 10.1136/oemed-2016-103673 VO 74 IS 8 A1 Enrico Pira A1 Canzio Romano A1 Francesca Donato A1 Claudio Pelucchi A1 Carlo La Vecchia A1 Paolo Boffetta YR 2017 UL http://oem.bmj.com/content/74/8/558.abstract AB Objective To investigate the long-term mortality of a cohort of Italian asbestos miners.Methods The cohort included 1056 men employed in a chrysotile mine between 1930 and 1990, who were followed up during 1946–2014, for a total of 37 471 person-years of observation. Expected deaths and SMRs were computed using national and local (after 1980, when available) reference.Results A total of 294 (27.8%) subjects were alive and at the end of follow-up, 722 (68.4%) were dead and 40 (3.8%) were lost to follow-up. The SMR for overall mortality was 1.35 (95%CI 1.25 to 1.45). The SMR for pleural cancer, based on seven observed deaths, was 5.54 (95% CI 2.22 to 11.4) and related to time since first exposure, but not to duration of employment, cumulative exposure or time since last exposure. The SMR for lung cancer was 1.16 (95% CI 0.87 to 1.52; 53 observed deaths), with no excess among workers with cumulative exposure below 100 fibre/mL-years (SMR 0.82; 95% CI 0.44 to 1.40).Conclusions The update of the follow-up of this cohort confirmed an increased mortality from pleural cancer mortality in miners exposed to chrysotile and a lack of significant increase in lung cancer mortality.