RT Journal Article SR Electronic T1 P158 Pregnant workers and the risk of exposure to parvovirus B19. literature review and action protocol JF Occupational and Environmental Medicine JO Occup Environ Med FD BMJ Publishing Group Ltd SP A173 OP A173 DO 10.1136/oemed-2016-103951.475 VO 73 IS Suppl 1 A1 Sierra, Noemí Prat A1 Tortajada, Maribel A1 Orpella, Xavier A1 Ramírez, Laura A1 Guerrero, Alejandro A1 González, Josep Anton YR 2016 UL http://oem.bmj.com/content/73/Suppl_1/A173.2.abstract AB Introduction The B19 (B19V) parvovirus is responsible for Erythema Infectiosum.Approximately 30 to 60% of the population in some studies and 66% in others, have IgG + for B19V, with an equal distribution between both sexes.The B19V is considered a biological risk agent in pregnant women, mainly because of its potential ability to produce fetal pathology, especially in the form of fetal hydrops and abortion, especially during the 2nd trimester.Various articles describe an occupational exposure risk to B19V in certain job positions, especially child care and health care workers.Methodology A PubMed literature review is undertaken to identify fetal and pregnant pathology associated with B19V infection prior to the formalisation of occupational health prevention protocols in workers pregnant and in fertile age. The inclusion criteria are: any articles in Spanish, English or French, on the effects of B19V on pregnancy and fetus. The study covers the period from 2000/01/01 to 2015/12/31. The search strategy was B19V AND pregnancy. 154 articles fulfilled the inclusion criteria.Results The disease primarily affects the fetus. The health problems identified were classified (number of citations), the most common fetal pathologies are fetal hydrops with 93 citations, fetal death with 70 and aplastic anaemia with 64. The rest of detected pathologies specified and grouped by systems are also listed.In pregnant women the most commong pathologies are anaemia, oedema and mirror sd with 6 citations each, and fulminant hepatitis and myocarditis with 2.Conclusions After the literature review, it’s determined the risk of both fetal and pregnant pathology due to exposure to B19V so a screening protocol by IgG and IgM is established for workers pregnant and in fertile age as well as prevention and monitoring of pregnant workers, repeating serology tests during pregnancy and assesing the risk presented by their workplace.