TY - JOUR T1 - Exposure to loud noise, bilateral high-frequency hearing loss and coronary heart disease JF - Occupational and Environmental Medicine JO - Occup Environ Med SP - 34 LP - 41 DO - 10.1136/oemed-2014-102778 VL - 73 IS - 1 AU - Wen Qi Gan AU - Jacqueline Moline AU - Hyun Kim AU - David M Mannino Y1 - 2016/01/01 UR - http://oem.bmj.com/content/73/1/34.abstract N2 - Objectives Bilateral high-frequency hearing loss is an indicator for chronic exposure to loud noise. This study aimed to examine the association between bilateral high-frequency hearing loss and the presence of coronary heart disease (CHD).Methods This study included 5223 participants aged 20–69 years who participated in the audiometry examination of the National Health and Nutrition Examination Survey 1999–2004. Bilateral high-frequency hearing loss was defined as the average high-frequency (3, 4 and 6 kHz) hearing threshold ≥25 dB in both ears. CHD was defined as self-reported diagnoses by doctors or other health professionals.Results Compared with those with normal high-frequency hearing, participants with bilateral high-frequency hearing loss were more likely to have CHD (OR 1.91; 95% CI 1.28 to 2.85) after adjustment for various covariates. This association was particularly strong for currently employed workers who were exposed to loud occupational noise (OR 4.23; 95% CI 1.32 to 13.55). For this subgroup, there was no significant association of CHD with unilateral high-frequency hearing loss, and unilateral or bilateral low-frequency hearing loss. Furthermore, there was no significant association of CHD with any types of hearing loss for participants who were not exposed to loud noise. Stratified analyses for participants exposed to loud noise showed that the observed association was particularly strong for those who were less than 50 years of age, less educated and current smokers.Conclusions On the basis of an objective indicator for personal chronic exposure to loud noise, this study confirmed that exposure to loud occupational noise is associated with the presence of CHD. ER -