PT - JOURNAL ARTICLE AU - Jacobsen, Gitte Højbjerg AU - Schlünssen, Vivi AU - Schaumburg, Inger AU - Sigsgaard, Torben TI - Cross-shift and longitudinal changes in FEV<sub>1</sub> among wood dust exposed workers AID - 10.1136/oemed-2011-100648 DP - 2013 Jan 01 TA - Occupational and Environmental Medicine PG - 22--28 VI - 70 IP - 1 4099 - http://oem.bmj.com/content/70/1/22.short 4100 - http://oem.bmj.com/content/70/1/22.full SO - Occup Environ Med2013 Jan 01; 70 AB - Objectives Acute lung function (LF) changes might predict an accelerated decline in LF. In this study, we investigated the association between cross-shift and longitudinal changes in forced expiratory volume in 1 s (FEV1) among woodworkers in a 6-year follow-up study. Methods 817 woodworkers and 136 controls participated with cross-shift changes of FEV1 at baseline and FEV1 and forced vital capacity at follow-up. Height and weight were measured and questionnaire information on respiratory symptoms, employment and smoking habits was collected. Wood dust exposure was assessed from 3572 personal dust measurements at baseline and follow-up. Cumulative wood dust exposure was assessed by a study-specific job exposure matrix and exposure time. Results The median (range) of inhalable dust at baseline and cumulative wood dust exposure was 1.0 (0.2–9.8) mg/m3 and 3.8 (0–7.1) mg year/m3, respectively. Mean (SD) for %ΔFEV1/workday and ΔFEV1/year was 0.2 (6.0)%, and −29.1 (41.8) ml. Linear regression models adjusting for smoking, age, height and weight change showed no association between cross-shift and annual change in FEV1 among woodworkers or controls. Including different exposure estimates, atopy or cross-shift change dichotomised or as quartiles did not change the results. Conclusions This study among workers exposed to low levels of wood dust does not support an association between acute LF changes and accelerated LF decline.