%0 Journal Article %A David Neasham %A Ahlem Sifi %A Kaspar Rene Nielsen %A Kim Overvad %A Ole Raaschou-Nielsen %A Anne Tjønneland %A Aurelio Barricarte %A Carlos A González %A Carmen Navarro %A Laudina Rodriguez Suarez %A Ruth C Travis %A Tim Key %A Jakob Linseisen %A Rudolf Kaaks %A Paolo Crosignani %A Franco Berrino %A Stefano Rosso %A Amalia Mattiello %A R C H Vermeulen %A H Bas Bueno-de-Mesquita %A Göran Berglund %A Jonas Manjer %A Sophia Zackrisson %A Goran Hallmans %A Beatrice Malmer %A Sheila Bingham %A Kay Tee Khaw %A Manuela M Bergmann %A Heiner Boeing %A Antonia Trichopoulou %A Giovanna Masala %A Rosario Tumino %A Eiliv Lund %A Nadia Slimani %A Pietro Ferrari %A Paolo Boffetta %A Paolo Vineis %A Elio Riboli %T Occupation and risk of lymphoma: a multicentre prospective cohort study (EPIC) %D 2011 %R 10.1136/oem.2009.048173 %J Occupational and Environmental Medicine %P 77-81 %V 68 %N 1 %X Objectives Evidence suggests that certain occupations and related exposures may increase the risk of malignant lymphoma. Farming, printing and paper industry, wood processing, meat handling and processing, welding, shoe and leather manufacturing and teaching profession are among the categories that have been implicated in previous studies. The relationship between occupation and malignant lymphoma has been investigated in a large European prospective study. Methods We investigated occupational risks for lymphomas in the European Prospective Investigation into Cancer and Nutrition (EPIC). The mean follow-up time for 348 555 subjects was 9 years (SD: 2 years). The analysis was based on 866 and 48 newly diagnosed cases of non-Hodgkin's lymphoma (NHL) and Hodgkin's lymphoma (HL). These were identified in the EPIC subcohorts with occupational data. Data on 52 occupations were collected through standardised questionnaires. Cox proportional hazard models were used to explore the association between occupation and risk of malignant lymphoma. Results The following occupations were positively associated with malignant NHL after adjustment for study centre, age, sex, socioeconomic status (SES), smoking and alcohol: butchers (HR=1.53, 95% CI 1.05 to 2.48, including multiple myeloma/plasmacytoma; HR=1.30, 95% CI 1.00 to 2.66, excluding multiple myeloma/plasmacytoma) and car repair workers (HR=1.50, 95% CI 1.01 to 2.00, including multiple myeloma/plasmacytoma; HR=1.51, 95% CI 1.01 to 2.31, excluding multiple myeloma/plasmacytoma). HL was associated with gasoline station occupation (HR=4.59, 95% CI 1.08 to 19.6). Conclusion The findings in this current study of a higher risk of NHL among car repair workers and butchers and a higher risk of HL among gasoline station workers suggest a possible role from occupationally related exposures, such as solvents and zoonotic viruses, as risk factors for malignant lymphoma. %U https://oem.bmj.com/content/oemed/68/1/77.full.pdf