RT Journal Article SR Electronic T1 Organisational justice and markers of inflammation: the Whitehall II study JF Occupational and Environmental Medicine JO Occup Environ Med FD BMJ Publishing Group Ltd SP 78 OP 83 DO 10.1136/oem.2008.044917 VO 67 IS 2 A1 Marko Elovainio A1 Jane E Ferrie A1 Archana Singh-Manoux A1 David Gimeno A1 Roberto De Vogli A1 Martin Shipley A1 Jussi Vahtera A1 Eric Brunner A1 Michael G Marmot A1 Mika Kivimäki YR 2010 UL http://oem.bmj.com/content/67/2/78.abstract AB Objectives Low organisational justice has been shown to be associated with increased risk of various health problems, but the underlying mechanisms remain unclear. We tested whether organisational injustice contributes to chronic inflammation in a population of middle-aged men and women.Methods This prospective cohort study uses data from 3205 men and 1204 women aged 35–55 years at entry into the Whitehall II study (phase 1, 1985–1988). Organisational justice perceptions were assessed at phase 1 and phase 2 (1989–1990) and circulating inflammatory markers C-reactive protein (CRP) and interleukin (IL)-6 at phase 3 (1991–1993) and phase 7 (2003–2004).Results In men, low organisational justice was associated with increased CRP levels at both follow-ups (phase 3 and 7) and increased IL-6 at the second follow-up (phase 7). The long term (phase 7) associations were largely independent of covariates, such as age, employment grade, body mass index and depressive symptoms. In women, no relationship was found between organisational justice and CRP or IL-6.Conclusions This study suggests that organisational injustice is associated with increased long-term levels of inflammatory markers among men.