@article {Li39, author = {W Li and R M Ray and D L Gao and E D Fitzgibbons and N S Seixas and J E Camp and K J Wernli and G Astrakianakis and Z Feng and D B Thomas and H Checkoway}, title = {Occupational risk factors for nasopharyngeal cancer among female textile workers in Shanghai, China}, volume = {63}, number = {1}, pages = {39--44}, year = {2006}, doi = {10.1136/oem.2005.021709}, publisher = {BMJ Publishing Group Ltd}, abstract = {Aims: To investigate whether occupational exposure to dusts and chemicals in the Chinese textile industry are associated with risk of nasopharyngeal cancer. Methods: Sixty seven nasopharyngeal carcinoma (NPC) cases identified during 1989{\textendash}98 and a random sample (n = 3188) of women were included in a case cohort study nested in a cohort of 267 400 women textile workers in Shanghai, China. A complete occupational history of work in the textile industry was obtained for each woman. A job exposure matrix developed by experienced industrial hygienists was used to assess exposures to specific dusts and chemicals. Results: Risk of NPC is associated with cumulative exposure to cotton dust. The hazard ratio for women cumulatively exposed to \>143.4 mg/m3 {\texttimes} years of cotton dust was 3.6 (95\% CI 1.8 to 7.2) compared with unexposed women. Trends of increasing risk were also found with increasing duration of exposure to acids and caustics (p = 0.05), and with years worked in dyeing processes (p = 0.06). Women who worked at least 10 years in dyeing processes had a 3.6-fold excess risk of NPC (95\% CI 1.0 to 12.1). Conclusions: Occupational exposure to cotton dust, acids, and caustics, and work in dyeing and printing jobs in the textile industry may have increased risk of NPC in this cohort.}, issn = {1351-0711}, URL = {https://oem.bmj.com/content/63/1/39}, eprint = {https://oem.bmj.com/content/63/1/39.full.pdf}, journal = {Occupational and Environmental Medicine} }