TY - JOUR T1 - Effect of farming environment on sensitisation to allergens continues after childhood JF - Occupational and Environmental Medicine JO - Occup Environ Med SP - 607 LP - 611 DO - 10.1136/oem.2004.014852 VL - 62 IS - 9 AU - H O Koskela AU - K K Happonen AU - S T Remes AU - J Pekkanen Y1 - 2005/09/01 UR - http://oem.bmj.com/content/62/9/607.abstract N2 - Aims: The farming environment in childhood has been reported to decrease the risk of sensitisation to allergens. The purpose of the present study was to explore whether later exposure to a farming environment also could affect this sensitisation. Methods: A population based sample of 202 women who did not live on a farm and 231 who did. The subjects filled in a questionnaire and underwent skin prick tests for several common and farming related allergens. Results: The prevalence of sensitisation to any of the allergens was similar in the two groups (37.1 v 34.6% (p = NS). However, compared with women who did not live on a farm, the women who lived on a dairy farm showed a low prevalence of sensitisation to pollens (4.4 v 17.3%, p = 0.01) and cats (3.5 v 10.4%, p = 0.047). The risk of sensitisation to pollens and pets was lowest among women with both a childhood and adulthood farming environment and was dose dependently associated with current contact with farm animals. However, this contact increased the risk of sensitisation to bovine dander. Conclusion: The farming environment may reduce sensitisation to common allergens also after early childhood. However, it may also increase sensitisation to farm allergens. ER -