RT Journal Article SR Electronic T1 Acute Toxicity and Skin Irritant Properties of Sulfolane JF British Journal of Industrial Medicine JO Br J Ind Med FD BMJ Publishing Group Ltd SP 302 OP 304 DO 10.1136/oem.23.4.302 VO 23 IS 4 A1 V. K. H. Brown A1 L. W. Ferrigan A1 D. E. Stevenson YR 1966 UL http://oem.bmj.com/content/23/4/302.abstract AB Sulfolane is a useful industrial solvent. The oral LD50 values were: rats, 1·7 to 2·7 g./kg.; mice, 1·9 to 2·5 g./kg., all deaths taking place within 24 hours. Rats showed no effects after 3·8 g./kg. had been applied to the skin. The compound did not irritate or sensitize the skins of guinea-pigs or rabbits and, undiluted, was almost without action on the eyes of rabbits.