PT - JOURNAL ARTICLE AU - V. K. H. Brown AU - L. W. Ferrigan AU - D. E. Stevenson TI - Acute Toxicity and Skin Irritant Properties of Sulfolane AID - 10.1136/oem.23.4.302 DP - 1966 Oct 01 TA - British Journal of Industrial Medicine PG - 302--304 VI - 23 IP - 4 4099 - http://oem.bmj.com/content/23/4/302.short 4100 - http://oem.bmj.com/content/23/4/302.full SO - Br J Ind Med1966 Oct 01; 23 AB - Sulfolane is a useful industrial solvent. The oral LD50 values were: rats, 1·7 to 2·7 g./kg.; mice, 1·9 to 2·5 g./kg., all deaths taking place within 24 hours. Rats showed no effects after 3·8 g./kg. had been applied to the skin. The compound did not irritate or sensitize the skins of guinea-pigs or rabbits and, undiluted, was almost without action on the eyes of rabbits.