81 e-Letters

published between 2006 and 2009

  • Chrysotile exposure and lung cancer
    Stuart A Levy

    September 17, 2007

    Editor Occupational and Environmental Medicine

    Hein et al reported an excess of lung cancer in a cohort of South Carolina textile workers attributed to chrysotile asbestos exposure(1). Information on smoking, the predominant risk factor for lung cancer, was not known. Table 2 in the publication shows an excess mortality from ischemic heart disease (SMR 1.39) and chronic obstructive...

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  • The IARC Monographs and the new Preamble
    Vincent James Cogliano

    I would like to clarify two points from the response by Drs Crosignani and Gennaro[1] on the IARC Monographs as a resource for precaution and prevention.[2] First, the new formaldehyde Monograph[3] strengthened the evaluation of formaldehyde, and it would be a mistake to ignore formaldehyde as a workplace or environmental health hazard. The Monograph raised the classification from "probably carcinogenic" (Group 2A) to...

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  • The IARC Monographs: a resource for precaution and prevention? The new Preamble does not fit.
    paolo crosignani

    In the last issue of OEM, Cogliano (1) presented the IARC Monographs as a tool both for precaution and prevention. If true in the past, the new Preamble severely impairs this potential.

    In fact, a new task for the working group has been introduced: “the target organ(s) or tissue(s) in which an increase in cancer was observed is identified” and “A statement that there is sufficient evidence is followed by a separ...

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  • Ischaemic heart disease among chrysotile textile workers
    Bengt Sjögren

    Letter to the editor regarding Follow-up study of chrysotile textile workers: cohort mortality and exposure-response by Hein MJ, Stayner LT, Lehman E, Dement JM in Occup Environ Med 2007; 64: 616-625.

    Bengt Sjögren MD, PhD, Work Environment Toxicology, Institute of Environmental Medicine, Karolinska Institutet, SE-177 77 Stockholm, Sweden, Phone +46 8 524 822 29, Fax +46 8 31 41 24, E-mail bengt.sjogren@ki...

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  • Urine not reliable assessment of uranium intake
    James P. Salsman

    Measuring uranium intake using urine isotope ratio studies has been known for a decade to only be accurate up to a few weeks after exposure.

    "Urine assay for uranium inhalation exposure can be useful, provided that measurements are made soon after a known acute intake. The urinary excretion rate falls substantially after exposure, particularly during the first few days. If urine analysis is carried out on a routi...

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  • World At Work: Evidence based risk management of nail dust in chiropodists and podiatrists
    Huw G Rees

    Dear Sir

    This paper is a valuable review of a neglected hazard (1). However, the following points deserve additional emphasis.

    There is limited evidence that exposure to keratin nail dust can cause allergic conditions. Guinea pigs inhaling aerosolised nail dust produced IgE against T. rubrum, and developed lung lesions similar to hypersensitivity pneumonitis (2). A high prevalence of wheeze has be...

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  • Authors response to editorial
    Helen C Francis

    We are writing in response to the editorial (1) relating to our previously published paper on a consensus study defining occupational asthma and confirming the diagnosis (2). We feel that the editorial reads more into the RAND consensus approach than the technique allows. The RAND process is a validated approach to develop consensus in situations where no gold standard or formal agreement exists. It is not possible to de...

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  • Mineral fibres and lung cancer
    Heikki Savolainen

    Dear Editor,

    This multicentre study confirms the idea that man made mineral fibres (1), with exception of refractory ceramic fibres (2), are not associated with lung cancer.

    Modern monitoring techniques would allow a more exact determination of fibre dose (1,2) so that a prospective study would be possible as to the malignant disease risk also at other sites than respiratory tract (3).

    1 Paana...

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  • Melanoma and dentist: only socioeconomic status?
    Beatriz Pérez-Gómez

    To the Editor:

    We have read the interesting paper from Adam Simning and Edwin van Wijngaarden about cancer in dentists. However, in their article, they attribute the increased skin cancer occurrence in this occupation to socioeconomic status.

    In this sense, we would like to point out that, at least in Sweden, our results showed a significant risk excess of melanoma in males dentists [1] and female...

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  • authors response to e-letters
    Helen C Francis

    We thank Dr Preece for his comments. We believe that he is justified in questioning the make up of the panel and that this has a significant bias for tertiary assessment of occupational lung disease. However our aim in performing this process was to get this group of experts to agree on "definitions” with a view to unifying the label at this later clinical stage of the process. In addition we hoped that the requirements...

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