232 e-Letters

  • Response to Boers et al: request for additional results on cardiovascular disease
    Olivier Humblet

    We read with great interest the recent publication by Boers et al (2010), in which they presented updated mortality results from an occupational cohort of Dutch chlorophenoxy herbicide manufacturing workers. The previous follow-up from this cohort (Hooiveld et al, 1998) reported a statistically significant dose-related increase in mortality from ischemic heart disease (IHD) with increasing levels of modeled TCDD exposur...

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  • 4-Chloro-ortho-toluidine is not present in cigarette smoke
    Elmar Richter

    Within the Introduction the authors wrongly state that 4-chloro-ortho -toluidine is present in cigarette smoke. Whereas ortho-toluidine has been repeatedly reported to be present in cigarette smoke, this has never been reported for 4-chloro-ortho-toluidine. ortho-Toluidine has also been implicated in bladder cancer in the rubber industry (Baan et al. Lancet Oncol. 9:322-323, 2008) and this was corroborated by results of a...

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  • Bias and caution
    David Gimeno

    Dear Editor

    A recent article by Daniels [1] in this journal presented occupational stress data from the 15 European Union (EU) countries.

    Cross- national comparisons contribute to our scientific understanding of how and why health-related indicators (i.e. stress) are unequally distributed across countries and provide clues and guidelines for researchers, policy makers and trade unions at the EU level. Howeve...

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  • Occupational exposure to solvents and risk of lymphoma subtypes: results from the Epilymph case-control study
    Gerhard Triebig

    Considering the temporal association between exposure to benzene and the later development of leukaemia it is questionable if this phenomena is also true for NHL.1 From several independent epidemiologic studies with consistent findings it can be concluded, that 10 to 15 years after exposure to benzene has been stopped, the risk of leukaemia is significantly less or even absent.2,3,4

    Assuming that the underlying...

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  • Response to an "ECHO" on workplace based faecal occult blood screening
    Andreas Zober

    In a recent short report, a summary of the results of a workplace based colorectal tumour-screening programme in UK was given.[1]

    During 2001-02 we organised a similar programme within BASF's – the world's largest chemical company – Ludwigshafen/Germany site. Our findings were published in a German language paper.[2] Our target group included all 13 265 actively working employees aged 45 years or above. Those exp...

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  • Long-term carcinogenesis bioassays in animals are poor predictors of cancer risk to humans
    Joseph Manuppello

    In his letter, Predicting chemicals causing cancer in animals as human carcinogens (Occup Environ Med 2010;67:720), Huff surprisingly finds opportunity to promote long-term carcinogenesis bioassays using animals in response to an editorial by Suarthana et al (Occup Environ Med 2009;66:713e14), Predicting occupational diseases. In their editorial, Suarthana et al generalize from the development of diagnostic models to pred...

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  • Radiation as a cause of mesothelioma.
    John H. Lange

    Dear Editor

    Atkinson et al,[1] reported “particularly among those monitored for plutonium exposure there was a significant excess mortality from cancer of the pleura”.

    However, they also note the lack of a trend for radiation dose. The authors’ suggest that these cancers are mostly mesothelioma and that asbestos is the likely causative agent. There is no mention of other agents that can cause mesothe...

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  • Re:Occupational exposure to solvents and risk of lymphoma subtypes: results from the Epilymph case-control study
    Pierluigi Cocco
    We thank Dr Triebig for his interesting comments on our article “Occupational exposure to solvents and risk of lymphoma subtypes: results from the Epilymph case-control study�.1,2 Epidemiological evidence is growing about the various etiological factors of specific lymphoma subtypes, and perhaps the different mechanisms involved.3 In our paper, we referred to previous reports suggesting an interaction o...
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  • Perecived risk from stress is not objective risk from stress
    Kevin Daniels

    Dear Editor

    Gimeno, Amick, Benavides and Benach [1] raise a number of issues with a paper recently published in Occupational and Environmental Medicine.[2] It is important that researchers cross-examine others’ findings and conclusions, as well as explain and defend their own findings and conclusions, so that debate can proceed that is both informed and useful for policy and practice.

    In the original...

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  • Re-employment of NHS staff following retirement on the grounds of ill-health
    Mark S Newson-Smith

    Dear Editor

    Pattani and colleagues present some interesting and useful findings in an area of great importance to the delivery of health care within the United Kingdom.[1] They note that “doctors were nearly four times more likely to return to work as health care assistants and support staff” and that “this may reflect more flexible working opportunities for highly skilled staff”. I would suggest that it might al...

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