1 e-Letters

published between 2018 and 2021

  • Excess additive risk of cataract incidence in radiologic technologists: alternative explanation

    Dose-dependent diagnostic efficiency and self-reporting related to a longer work history and hence to cumulative dose could explain the above-average risk of cataracts in radiologic technologists [1]. Of concern was the discrepancy between the findings for cataract history and cataract surgery, where risks for the latter were somewhat lower and generally not significant [1]. A similar pattern of significant excess relative risk (ERR) for cataract and non-significant ERR for cataract surgery has also been reported in the Mayak nuclear workers. [2,3]. This agrees with the concept of dose-dependent diagnostic efficiency with detection of mild cases not requiring surgery. Among the various groups that have been studied for radiation-associated cataract, a significant ERR for cataract surgery has been reported only in the Japanese atomic bomb survivors [4-6], where the effect of the acute exposure could indeed have taken place. More details [7].
    1. Little MP, Cahoon EK, Kitahara CM, Simon SL, Hamada N, Linet MS. Occupational radiation exposure and excess additive risk of cataract incidence in a cohort of US radiologic technologists. Occup Environ Med. 2020 Jan;77(1):1-8. doi: 10.1136/oemed-2019-105902.
    2. Azizova TV , Hamada N , Grigoryeva ES , et al. . Risk of various types of cataracts in a cohort of Mayak workers following chronic occupational exposure to ionizing radiation. Eur J Epidemiol2018;33:1193–204.doi:10.1007/s10654-018-0450-4
    3. Azizova TV , Hamad...

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