Article Text

Download PDFPDF
Letter
Maternal occupational exposure to solvents and gastroschisis in offspring: are gene–environment interactions playing a role?
  1. Qing Chang1,
  2. Hong-Lin Chen2
  1. 1Wuxi No.8 People's Hospital and Wuxi Occupational Disease Hospital, Wuxi, Jiangsu Province, China
  2. 2School of Public Health, Nantong University, Nantong, Jiangsu Province, China
  1. Correspondence to Dr Qing Chang, Wuxi No.8 People's Hospital and Wuxi Occupational Disease Hospital, Wuxi City, Jiangsu Province, China; q_chang{at}sohu.com

Statistics from Altmetric.com

In a recent issue of Occupational and Environmental Medicine, a study by Spinder et al1 reported the results of the association between maternal occupational exposure to solvents and gastroschisis in offspring. Spinder et al found that among 879 cases and 7817 controls, the overall prevalence of periconceptional solvent exposure was 7.3% and 7.4%, respectively, and exposure to solvent versus no exposure was not associated with gastroschisis after adjusting for maternal age (OR 1.00, 95% CI 0.75 to 1.32), nor was an association noted for solvent classes.1 However, we think this conclusion should be treated with caution.

Gene–environment …

View Full Text

Footnotes

  • Contributors Both authors contributed equally.

  • Funding This research received a grant from Wuxi City Key Clinical Specialty (Occupational Disease) Construction Plan.

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Provenance and peer review Not commissioned; internally peer reviewed.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.