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This study of endotypes responsible for the development of irritant induced occupational asthma raises questions as to what is meant by a respiratory irritant.1 Classifying an exposure as irritant usually implies that the effect is non-specific, that is, all similar asthmatics would react to the exposure whether they have had previous exposure to the agent or not. For instance, sulphur dioxide is a respiratory irritant, the exposure needed to provoke asthma is correlated …
Contributors The original draft was written by SB. All authors amended the original text and approved the final document. It represented the views of the occupational lung disease team.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Provenance and peer review Commissioned; internally peer reviewed.