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Response to Tomenson’s letter on ‘Lung cancer mortality in the French cohort of titanium dioxide workers: some aetiological insights’
  1. Irina Guseva Canu1,
  2. Danièle Luce2,
  3. Kurt Straif3,4
  1. 1 Department of Occupational and Environmental Health, Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, VD, Switzerland
  2. 2 University of Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMRS 1085, Pointe-à-Pitre, France
  3. 3 Boston College, Chestnut Hill, Massachusetts, USA
  4. 4 ISGLOBAL, Barcelona, Spain
  1. Correspondence to Professor Irina Guseva Canu, Department of Occupational and Environmental Health, University of Lausanne, Lausanne 1066, Switzerland; irinacanu{at}

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We thank the editor for giving us the opportunity to respond to the points raised by Tomenson.1 Further, we would like to thank Tomenson for making publicly available parts of the so far unpublished report to the sponsors (the Titanium Dioxide Manufacturers Association, for which he provides consultancy services), including particularly the positive dose–response data for the French subcohort (reanalysed in our paper).2

As clearly described in the Methods and in the Results sections of our short report, the cumulative exposure to TiO2 was lagged by 10 years. Obviously, this also affects the number of unexposed …

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  • Contributors All authors drafted the manuscript and agreed on the submitted version.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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