Objective This study aims to explore the association between physical activity and high-sensitivity C reactive protein, based on different types of physical activity—occupational and leisure time.
Methods Using cross-sectional data from the Korea National Health and Nutrition Examination Survey 2015–2018, we explored the association between different types of self-reported physical activity and high levels of high-sensitivity C reactive protein (>3 mg/L). We estimated the ORs for high-level high-sensitivity C reactive protein using multiple logistic regression models after adjusting for covariates from 12 970 eligible subjects (mean age 44.8).
Results Compared with subjects who did not engage in moderate-to-vigorous level of occupational physical activity (OPA), the group that engaged in moderate-to-vigorous level of OPA showed a significantly high OR (1.32, 95% CI (1.03 to 1.69)), whereas the group that engaged in moderate-to-vigorous level of leisure-time physical activity (LPA) yielded a low OR (0.84, 95% CI (0.69 to 1.01)). The group that engaged in moderate-to-vigorous level of OPA but not LPA showed a significantly high OR (1.76, 95% CI (1.27 to 2.45)) compared with subjects who engaged in moderate-to-vigorous level of LPA but not in OPA.
Conclusions OPA is directly associated with high C reactive protein levels, suggesting that it increases the risk of inflammation.
- occupational health practice
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Contributors JL made the study idea. JL conducted the statistical analysis and wrote the first draft. D-WL, M-YK, T-WJ, YML and H-RK interpreted the results and revised the reviewed the literature. M-YK and JL revised the manuscript. All authors have read and approved the final version of the submitted manuscript.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient consent for publication Not required.
Ethics approval Data collection was performed after approval by the Institutional Review Board (IRB) of the Korean Centers for Disease Control and Prevention (approval number: 2018-01-03-P-A). This study was confirmed as an exemption of ethical review by the IRB of Seoul St. Mary’s Hospital, the Catholic University of Korea (study number: KC20ZISI0159).
Provenance and peer review Not commissioned; externally peer reviewed.
Data availability statement Data are available in a public, open access repository. The data for this study were accessed through the KNHANES homepage (https://knhanes.cdc.go.kr/knhanes/eng/index.do).
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