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Original research
Pulmonary function and high-resolution computed tomography in outdoor rock drillers exposed to crystalline silica
  1. Bente Ulvestad1,
  2. Mariann Ulvestad2,
  3. Nils Petter Skaugset3,
  4. Trond Mogens Aaløkken4,
  5. Anne Günther4,
  6. Thomas Clemm5,
  7. May Brit Lund2,
  8. Dag Gunnar Ellingsen3
  1. 1 Department of Occupational Medicine and Epidemiology, The Natioanal Institute of Occupational Health, Oslo, Norway
  2. 2 Department of Respiratory Medicine, Oslo University Hospital, Oslo, Norway
  3. 3 Department of Chemical and Biological Work Environment, National Institute of Occupational Health, Oslo, Norway
  4. 4 Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway
  5. 5 Department of Occupational Health Services, Mesta AS, Bergen, Norway
  1. Correspondence to Bente Ulvestad, The Natioanal Institute of Occupational Health, Oslo 0363, Norway; bente.ulvestad{at}stami.no

Abstract

Objectives Chronic obstructive pulmonary disease and silicosis are associated with exposure to crystalline silica. We determined the exposure to respirable crystalline silica and estimated exposure–response relationships between cumulative exposure and pulmonary function in outdoor rock drillers.

Methods 136 rock drillers and 48 referents were recruited from three heavy construction companies. 98 air samples were collected by personal sampling for determination of respirable particulate matter and crystalline silica. Information about individual job tasks, type of drilling equipment and years of exposure in different job categories was obtained by interview. Cumulative exposure to crystalline silica was calculated for all workers. Pulmonary function was assessed by spirometry. A subgroup of 39 subjects with high cumulative exposure to crystalline silica underwent high-resolution computed tomography (HRCT).

Results Cumulative exposure (mean (min–max)) to crystalline silica was 0.69 mg٠years m–3 (0.01–5.89) in the exposed group. Mean time of exposure among rock drillers was 10.7 years (1–42). Compared with referents, the rock drillers had a lower forced expiratory volume in one second/forced vital capacity ratio (79.4 vs 81.4, p<0.05) and maximal mid-expiratory flow% (85.6 vs 93.9, p<0.05). Further, by stratifying the exposed workers into three equally large groups, a dose–response relationship was demonstrated in the highest exposed group, also in never smokers, at a mean cumulative exposure of 21.7 years at 0.08 mg٠m–3/years. Silicosis was not detected in HRCT, but other patterns of fibrosis and emphysema were seen.

Conclusions Outdoor rock drillers exposed to crystalline silica had significantly lower pulmonary function than referents, and signs of airflow obstruction. Silicosis was not detected.

  • epidemiology
  • hygiene / occupational hygiene
  • respiratory
  • silicosis
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Footnotes

  • Contributors BU, NPS, MBL and DGE designed the study. MU, TC, BU and NPS were responsible for data collection. AG and TMA reviewed the HRCT. BU and DGE were responsible for statistical analyses and drafting the manuscript. The manuscript was critically reviewed and approved by all authors.

  • Funding The study was carried out with financial support from The Fund for Regional Safety Representatives for Building and Construction Activities (Norway).

  • Competing interests None declared.

  • Patient consent for publication Informed written consent

  • Ethics approval This study was approved by South East Norwegian Regional Ethical Committee for Medical Research (REK) (2015/2116).

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data availability statement Data are available upon reasonable request. Data are available in a secure database.

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