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Original article
Melanoma incidence in Australian commercial pilots, 2011–2016
  1. Catherine M Olsen1,2,
  2. Kyoko Miura3,
  3. Jean Claude Dusingize1,
  4. Ian Hosegood4,
  5. Russell Brown4,
  6. Michael Drane5,
  7. Peter Clem6,
  8. Jerry Marsden7,
  9. Rick Tinker8,
  10. Ken Karipidis8,
  11. Minas Coroneo9,
  12. Adele C Green3,10
  1. 1 Cancer Control Group, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia
  2. 2 Faculty of Medicine, University of Queensland, Brisbane, Australia
  3. 3 Cancer and Population Studies Group, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia
  4. 4 Qantas Airlines Limited, Sydney, Australia
  5. 5 Air New Zealand, Auckland, New Zealand
  6. 6 Civil Aviation Safety Authority, Canberra, Australia
  7. 7 University Hospital, Birmingham, UK
  8. 8 Australian Radiation Protection and Nuclear Safety Agency, Melbourne, Victoria, Australia
  9. 9 Department of Ophthalmology, University of New South Wales at Prince of Wales Hospital, Sydney, Australia
  10. 10 CRUK Manchester Institute and Faculty of Biology Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK
  1. Correspondence to Dr Catherine M Olsen, Cancer Control Group, QIMR Berghofer Medical Research Institute, Herston, QLD 4006, Australia; catherine.olsen{at}qimrberghofer.edu.au

Abstract

Objectives Occupational exposure to cosmic and ultraviolet radiation may increase airline pilots’ risk of cutaneous melanoma. Meta-analyses of available data show a higher than average incidence of melanoma in airline pilots, but the most recent systematic review revealed that few contemporary data are available. Moreover, all relevant studies have been conducted in Northern Hemisphere populations. We therefore aimed to examine if Australian commercial pilots have a raised incidence of melanoma compared with the general population.

Methods We examined all melanoma histologically diagnosed among Australian-licensed commercial pilots in the period 2011–2016 by manually reviewing de-identified data in the medical records system of the Australian Civil Aviation Safety Authority. We estimated age-specific incidence rates and compared these with corresponding population rates using standardised incidence ratios (SIRs) as measures of relative risk. Expected numbers were calculated by multiplying age- and calendar period-specific person-years (PYs) with corresponding rates from the entire Australian population; 95% CI were calculated assuming a Poisson distribution of the observed cases.

Results In this cohort of Australian-licensed commercial pilots observed for 91 370 PYs, 114 developed a melanoma (51 invasive, 63 in situ). More than 50% of melanomas occurred on the trunk, and the predominant subtype was superficial spreading melanoma. The SIR for invasive melanoma was 1.20 (95% CI 0.89 to 1.55) and for melanoma in situ, 1.39 (95% CI 1.08 to 1.78).

Conclusion Australian-licensed commercial pilots have a modestly raised risk of in situ melanoma but no elevation of invasive melanoma compared with the general population.

  • melanoma
  • aviation medicine
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Footnotes

  • Contributors CMO, KM and ACG designed the study and directed its implementation. JCD, MD and PC gathered the data. CMO and JCD performed the statistical analysis. ACG, CMO, KM, IH, RB, RT, KK and MD obtained funding for the study. CMO and ACG drafted the manuscript, and all other authors (KM, JCD, IH, RB, MD, PC, JM, RT, KK and MC) revised the manuscript providing important intellectual content.

  • Funding This work was funded by a grant from the Australasian Society of Aerospace Medicine (ASAM).

  • Competing interests None declared.

  • Ethics approval The study was approved by the Human Research EthicsCommittee of the QIMR Berghofer Medical Research Institute.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Not required.

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