Article Text

Download PDFPDF

1375 Association between age-stratified obstructive sleep apnea syndrome and obesity
  1. S Nogami1,
  2. H Seki2,
  3. K Maruyama3,
  4. T Tanigawa4,
  5. N Suganuma1
  1. 1Department of Environmental Medicine, Kochi Medical School, Kochi University, Nankoku, Japan
  2. 2Department of otorhinolaryngology, Niyodo Hospital, Ino, Japan
  3. 3Laboratory of Community Health and Nutrition, Special Course of Food and Health Science, Department of Bioscience, Graduate School of Agriculture, Ehime University, Matsuyama, Japan
  4. 4Department of Public Health, Graduate School of Medicine, Juntendo University, Tokyo, Japan


Introduction Obstructive sleep apnea (OSA) among public-transportation drivers becomes a social concern in a certain number of traffic accidents. Major risk factors of OSA were reportedly obesity and ageing; however, age stratified relationship between OSA and risk factors have yet to be evaluated. This study aimed to evaluate the association between OSA and obesity stratified by age-groups.

Methods One hundred and fifty-five bus drivers were screened by the flow sensor method, to detect subject with a respiratory disturbance index (RDI) more than 15. Then, portable polysomnography (PSG) tests were performed to measure an apnea hypopnea Index (AHI): subjects with AHI≥40 were diagnosed as OSA; for those with 20≤AHI<40 full PSG tests were performed. Portable PSG AHI≥20 was diagnosed as OSA. Relationship between OSA and BMI were statistically compared in three age-groups; younger than 40, 40 to 49, and 50 and older by the logistic regression analysis and unpaired t-test.

Result Of the 152 subjects (45.2±9.3 year-old, BMI 24.5±4.5) after excluding 4 subjects (unexamined by PSG), 55 subjects showed RDI>15 by the screening test and underwent PSG. 25 subjects were diagnosed as a definite OSA. BMI was significantly associated with OSA with OR of 1.17 (95% CI: 1.06 to 1.29). ORs for OSA become greater as the age increased showing greatest OR in 50 and older (OR 5.15, 95% CI: 1.17 to 22.8). Mean BMI of OSA subjects with younger than 40 was greater than that of non-OSA (BMI 34.8±9.3 and 23.1±5.2, respectively, p=0.0012), however, no difference was found in those with 40–49 and 50 and older.

Discussion The result suggests weight reduction may more effective for younger drivers. Obesity of the drivers is highly associated with OSA for younger than 40, while ageing is more correlated with OSA than obesity for 50 and older.

  • Sleep Apnea
  • Obesity
  • Age

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.