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484 Radon and risk of lung cancer in apulia region southern italy
  1. GM Ferri,
  2. D Cavone,
  3. G Intranuovo,
  4. F Birtolo,
  5. P Tricase,
  6. R Fuso,
  7. L Vimercati
  1. University of Bari, Italy, Interdisciplinary Department of Medicine (DIM), Section ‘B. Ramazzini’, Universitary Regional Hospital ‘Policlinico – Giovanni XXIIIth’, Unit of Occupational Medicine


Introduction Radon is a naturally occurring radioactive gas and a level 1 carcinogen by IARC. It acts synergistically with cigarette smoke to cause lung cancer. The limit of 300 Bq/m3 is envisaged, both for working environments and for living environments, from the new European Directive on the Protection of Ionising Radiant (‘Basic Safety Standards’ – Council Directive 2013/59/Euratom, published in OJ L −13 of 17/1/2014), which will be transposed by Member States of the European Union by the deadline of 06 February 2018.

Method we studied the association between different building, occupational and geologic characteristics and high levels of radon concentrations (above the 75% percentile). Also the lung cancer death rates for the exposure to Radon was assessed by means of the REID method (Nezahat Hunter, 2015) related to different smoking habits groups. The data collection was carried out using Apulia observed radon data collected by regional environmental protection agency (Arpa), in the provinces of Bari and Lecce and other sources.

Results The preliminary data showed an increase of risk to observe Radom mean values above the 75th percentile (100 Bq·m-3) associated to years of building above 1972 (OR=2.28 to OR=4.70), elevated number of rooms (OR=2.16), Non cement walls (OR=2.6). The risk rate due to residential radon will be calculated and differentiated for Continuing smokers, Ex-smokers and Never smokers. The calculations of specific lung cancer rates will be based on the REID method.

Discussion Radon exposure is the second cause of lung cancer. Many lung cancer cases could be prevented in Apulia by reducing indoor radon and smoking habits. The regional and provincial health authorities would be benefited by improved testing for radon and subsequent home remediation rates. Safety structural building procedures could be useful for lung cancer prevention.

  • radon
  • lung cancer
  • Apulia Region

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