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Occupational Medicine
144 Smoking adjusted incidence of bladder cancer using proxy smoking from lung cancer in nordic males
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  1. Kishor Hadkhale1,
  2. Jan Iver Martinsen2,
  3. Elisabete Weiderpass2,3,4,5,
  4. Kristina Kjaerheim2,
  5. Elsebeth Lynge6,
  6. Pär Sparen5,
  7. Laufey Tryggvadottir7,8,
  8. Eero Pukkala1,9
  1. 1University of Tampere, Tempere, Finland
  2. 2Department of Research, Cancer Registry of Norway, Institute of Population-Based Cancer Research,Oslo, Norway
  3. 3Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway
  4. 4Genetic Epidemiology Group, Folkhälsan Research Centre, Helsinki, Finland
  5. 5Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
  6. 6Center for Epidemiology and Screening, Institute of Public Health, University of Copenhagen, Copenhagen, Denmark
  7. 7Icelandic Cancer Registry, Reykjavik, Iceland
  8. 8Faculty of Medicine, University of Iceland, Reykjavik, Iceland
  9. 9Finnish Cancer Registry, Institute for Statistical and Epidemiological Cancer Research, Helsinki, Finland

Abstract

Objectives The objective of this study was to observe the occupational variation in risk of bladder cancer that is not attributable to smoking.

Methods In the Nordic Occupational Cancer study (NOCCA), 1 11 458 cases of bladder cancer and 2 08 297 cases of lung cancer cases were observed among men in Denmark, Finland, Iceland, Norway and Sweden during 1961–2005. The expected numbers of bladder cancer in occupational category were corrected with smoking prevalence estimated on the basis of lung cancer risk in the category. Crude and smoking-adjusted standardised incidence ratios (SIR) with 95% confidence intervals (CI) were calculated for each occupation.

Results The smoking-adjusted SIR for most of the occupations was closer to 1.00 than the unadjusted SIR. It signifies the role of smoking as a risk factor of both bladder and lung cancers. Highest statistically significant smoking-adjusted SIRs were observed among chimney sweeps (SIR 1.33, 95% CI: 1.08 to 1.61), waiters (1.18, 1.04–1.34) hairdressers (1.16, 1.04–1.28), cooks and stewards (1.13, 1.01–1.27) and printers (1.10, 1.03–1.06).

Conclusion Smoking is a strong risk factor bladder cancer but there are other factors in some specific occupations in addition to smoking. The occupational variation in risk of bladder cancer is small when adjusted for smoking.

https://doi.org/10.1136/oemed-2018-ICOHabstracts.1056

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