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Epidemiology
1554 Estimation of the global burden of mesothelioma deaths from incomplete national mortality data
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  1. Odgerel Chimed-Ochir1,
  2. Ken Takahashi2,
  3. Tom Sorahan3,
  4. Tim Driscoll4,
  5. Christina Fitzmaurice5,
  6. Makoto Yoko-o1,
  7. Kittisak Sawanyawisuth6,
  8. Sugio Furuya7,
  9. Fumihiro Tanaka8,
  10. Seichi Horie9,
  11. Nico van Zandwijk2,
  12. Jukka Takala10
  1. 1Department of Environmental Epidemiology, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Kitakyushu, Japan
  2. 2Asbestos Diseases Research Institute, Concord Clinical School, University of Sydney, Sydney, Australia
  3. 3Institute of Applied Health Research, University of Birmingham, Birmingham, UK
  4. 4School of Public Health, University of Sydney, Sydney, Australia
  5. 5Department of Medicine, Division of Hematology, Institute for Health Metrics and Evaluation, Washington, USA
  6. 6Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
  7. 7Japan Occupational Safety and Health Resource Center, Tokyo, Japan
  8. 8Second Department of Surgery, University of Occupational and Environmental Health, Kitakyushu, Japan
  9. 9Department of Health Policy and Management, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Kitakyushu, Japan
  10. 10Workplace Safety and Health Institute, Ministry of Manpower, Singapore

Abstract

Introduction Mesothelioma, one of the occupational cancer, is increasingly recognised as a global health issue and the assessment of its global burden is warranted.

Objectives To descriptively analyse national mortality data and to use reported and estimated data to calculate the global burden of mesothelioma deaths.

Methods For the study period of 1994 to 2014, we grouped 230 countries into 59 countries with quality mesothelioma mortality data suitable to be used for reference rates, 45 countries with poor quality data, and 126 countries with no data, based on the availability of data in the WHO Mortality Database. To estimate global deaths, we extrapolated the gender- and age-specific mortality rates of the countries with quality data to all other countries.

Results The global numbers and rates of mesothelioma deaths have increased over time. The 59 countries with quality data recorded 15 011 mesothelioma deaths per year over the three most recent years with available data (equivalent to 9.9 deaths per million per year). From these reference data, we extrapolated the global mesothelioma deaths to be 38 400 per year, based on extrapolations for asbestos use.

Conclusions Although the validity of our extrapolation method depends on the adequate identification of quality mesothelioma data and appropriate adjustment for other variables, our estimates can be updated, refined, and verified because they are based on commonly accessible data and are derived using a straightforward algorithm. Our estimates are within the range of previously reported values but higher than the most recently reported values.

  • Asbestos
  • Mesothelioma
  • Epidemiology

https://doi.org/10.1136/oemed-2018-ICOHabstracts.373

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