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0125 The Effects of Acute and Chronic Mental Stress on Cardiac Function
  1. Mark Wilson,
  2. Lorraine Conroy
  1. University of Illinois at Chicago, Chicago, IL, USA


Objectives The main objective of this study is to investigate the effects of chronic and acute stress on blood pressure, heart rate variability and an indicator of cardiac contractility. The study also aims to describe the degree to which various demographic and lifestyle factors modify the observed effect.

Method Chronic stress was assessed with a validated questionnaire, the Perceived Stress Scale. Acute stress was the level of stress experienced from the performance of a simple mental challenge on a scale from 1–100. Heart rate variability is calculated from heart rate measurements recorded via a heart rate monitor. Cardiac contractility index is derived from the amplitude ratio of the first to second heart sounds, as recorded with an electronic stethoscope. Measurements for each of the parameters were taken before and after performance of the task. Pre-task measurements were used as baseline data and related to reported chronic stress levels. Acute stress levels were compared with the difference between pre- and post-task cardiac measurements.

Results Average acute stress level was 17/100. A statistically significant increase in cardiac contractility index was found for acute stress, while no significant change in either HRV or heart rate was noted. Subjects with high chronic stress showed a significantly reduced cardiac contractility than those with low chronic stress, while no difference in HRV was found between groups.

Conclusions Acute and chronic stress exerts differing inotropic effects on the heart, while no chronotropic effect was observed.

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