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Metabolic disease and shift work: Is there an association? An analysis of NHANES data for 2007–2008
  1. Prasanna Santhanam,
  2. Henry K Driscoll,
  3. Todd W Gress,
  4. Rodhan Khthir
  1. Department of Internal Medicine, Marshall University School of Medicine, Huntington, West Virginia, USA
  1. Correspondence to Dr Prasanna Santhanam, Department of Internal Medicine, Marshall University School of Medicine, 1249 15th Street, Suite 300, Huntington, WV 25701, USA; prasanna{at}

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Previous epidemiological studies have shown that shift work is associated with higher levels of obesity and diabetes, possibly related to physiological maladaptation as a direct result of sleeping and eating at abnormal circadian times.1 In a previously performed cross-sectional study, shift work was associated with higher levels of triglycerides, lower levels of high-density lipoprotein cholesterol, and higher odds of metabolic syndrome in a multiple logistic regression analysis (OR 2.4; 95% CI 1.1 to 5.0).2 We performed an analysis of the cross-sectional NHANES data3 for 2007–2008 and compared the different metabolic parameters between regular daytime workers and shift workers. Shift workers included …

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  • Competing interests None.

  • Ethics approval Marshall University IRB.

  • Provenance and peer review Not commissioned; internally peer reviewed.