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Original article
Maternal occupational exposure to organic solvents during early pregnancy and risks of neural tube defects and orofacial clefts
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Other responses

  • Published on:
    Re:The study of the relation between maternal occupational exposure to solvents and birth defects should include oxygenated solvents (authors' response)
    • Tania A. Desrosiers
    • Other Contributors:
      • Christina C. Lawson, Robert E. Meyer, Martha A. Waters, Edwin van Wijngaarden, Peter H. Langlois, Paul A. Romitti, Adolfo Correa, Andrew F. Olshan

    We appreciate the interest of Dr. Garlantezec and colleagues in our article on the association between maternal occupational exposure to organic solvents (chlorinated, aromatic and Stoddard) and birth defects. We reported a positive association between chlorinated solvents and neural tube defects, particularly spina bifida; we did not observe an association between solvent exposure and orofacial clefts.

    As noted...

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    Conflict of Interest:
    None declared.
  • Published on:
    The study of the relation between maternal occupational exposure to solvents and birth defects should include oxygenated solvents

    We read with interest the report by Desrosiers et al of the association between maternal occupational exposure to organic solvents and some birth defects [1]. Their case-control study examined occupational exposure to three classes of solvents (chlorinated, aromatic and Stoddard) and found one association -- between neural tube defects (mainly spinal bifida) and maternal occupational exposure to chlorinated solvents, but n...

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    Conflict of Interest:
    None declared.