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Re: The study of the relation between maternal occupational exposure to solvents and birth defects should include oxygenated solvents (authors’ response)
  1. Tania A Desrosiers1,
  2. Christina C Lawson2,
  3. Robert E Meyer3,
  4. Martha A Waters2,
  5. Edwin van Wijngaarden4,
  6. Peter H Langlois5,
  7. Paul A Romitti6,
  8. Adolfo Correa7,
  9. Andrew F Olshan1
  1. 1Department of Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, North Carolina, USA
  2. 2National Center for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, Ohio, USA
  3. 3North Carolina Birth Defects Monitoring Program, State Center for Health Statistics, Raleigh, North Carolina, USA
  4. 4Department of Community and Preventative Medicine, University of Rochester Medical Center, Rochester, New York, USA
  5. 5Texas Department of State Health Services, Birth Defects Epidemiology and Surveillance Branch, Austin, Texas, USA
  6. 6Department of Epidemiology, University of Iowa College of Public Health, Iowa City, Iowa, USA
  7. 7University of Mississippi Medical Center, Jackson, Mississippi, USA
  1. Correspondence to Dr Tania A Desrosiers, Department of Epidemiology, University of North Carolina Gillings School of Global Public Health, Campus Box 7435, Chapel Hill, NC 27599, USA; ta_desrosiers{at}

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We appreciate the interest of Dr Garlantézec et al in our article on the association between maternal occupational exposure to organic solvents (chlorinated, aromatic and Stoddard) and birth defects.1 We reported a positive association between chlorinated solvents and neural tube defects, particularly spina bifida; we did not observe an association between solvent exposure and orofacial clefts.2

As noted in their comment, our …

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  • Competing interests None.

  • Provenance and peer review Not commissioned; internally peer reviewed.