Article Text

Download PDFPDF
The IARC Monographs: a resource for precaution and prevention
  1. Vincent James Cogliano
  1. Correspondence to:
 Dr V J Cogliano
 International Agency for Research on Cancer, 150 cours Albert Thomas, 69008 Lyon, France; cogliano{at}

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Commentary on the editorial by Martuzzi (see page 569)

In an excellent discussion, Marco Martuzzi describes the precautionary principle as meaning that scientific uncertainty must not be used as a reason to delay taking action.1 Deeply rooted in the history of public and environmental health, the precautionary principle has been embraced by ministers of health and environment across Europe. Martuzzi asserts that precaution is especially needed in areas fraught with complexity and uncertainty, for threats that may be irreversible or felt across generations, or when technological or societal change outpaces the accumulation of data.

Martuzzi is correct that the role of science is central to the application of the precautionary principle, but “caution” means something different in science. The hypothesis testing at the core of the scientific method tends to avoid false positives and tolerate false negatives. To illustrate, epidemiologists make a strong distinction between the terms “association” and “causal association”. The latter is used only when there are studies of high quality and a rigorous examination shows that other factors are unlikely to explain an association.2 There are also inherent limitations to what epidemiology is able …

View Full Text


  • Competing interests: None.

Linked Articles