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    Occupational cancer II

    O8.1 GENDER DIFFERENCES OF BLADDER CANCER RISK IN SPANISH TEXTILE WORKERS

    C. Serra1,2, M. Kogevinas3, D. Turuguet3, F. Fernandez3, P. Stewart4, N. Malats3, D. Silverman4, N. Rothman4, A. Tardon5, R. Garcia-Closas6, A. Carrato7, G. Castaño-Vinyals3, M. Dosemeci4.1Pompeu Fabra University, Barcelona, Spain; 2Corporació Parc Tauli, Sabadell, Spain; 3Municipal Institute of Medical Research, Barcelona, Spain; 4National Cancer Institute, Bethesda, USA; 5Universidad de Oviedo, Spain; 6Hospital Universitario de Canarias, Tenerife, Spain; 7Hospital General de Elche, Spain

    Introduction: Several occupations and exposures within the textile industry in Spain have been found to be associated with bladder cancer. Compared with other industries, a relatively high proportion of women is employed in textiles. We explored whether there are any differences of the risk of bladder cancer between men and women who worked in the textile industry.

    Methods: We conducted a hospital based case control study in Spain between 1998 and 2001, including 1226 cases of bladder cancer and 1271 controls (87% males). Lifetime occupational history was recorded through a computer assisted personal interview and exposures in the textile industry were assessed by a detailed modular questionnaire. Occupations, specific locations, tasks, and materials used within the industry were recorded. We did stratified analysis by sex and odds ratios (OR) and 95% confidence intervals (CI) were adjusted for age, region, other high risk occupations, and smoking.

    Results: Among a total of 248 identified textile workers 49 (20%) were women. Occupations with a high proportion of women were tailors (55%), spinners (32%), and weavers (25%). Risk estimates for bladder cancer were higher for women than men for all major textile occupations with sufficient numbers of women and for exposures associated with bladder cancer, such as: spinners …

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