Article Text

Download PDFPDF

Twin frequency and industrial pollution in different regions of Hesse, Germany
Free
  1. N Obi-Osius1,
  2. B Misselwitz2,
  3. W Karmaus3,
  4. J Witten4
  1. 1Epidemiological Working Group of the Ministry of Environment and Health and the Institute for Medical Biometry and Epidemiology, University Hospital Hamburg-Eppendorf, Germany
  2. 2Institute of Quality Assurance of Hesse, Eschborn/Frankfurt, Germany
  3. 3Department of Epidemiology, Michigan State University, East Lansing, USA
  4. 4Ministry of Social Welfare of Hesse, Department of Health, Wiesbaden, Germany
  1. Correspondence to:
 Dipl. Biol. N Obi-Osius
 Epidemiological Working Group, Ministry of Environment and Health and the Institute for Medical Biometry and Epidemiology, University Hospital Hamburg-Eppendorf, Winterhuder Weg 29, 22085 Hamburg, Germany; osiusuke.uni-hamburg.de

Abstract

Aims: To investigate whether twinning occurs more frequently in residents in the vicinity of a toxic waste incinerator (TWI).

Methods: Within a longitudinal environmental study that addressed child health second grade school children and their parents were recruited. The proportion of twinning in the TWI region was compared with two comparison areas. In a second confirmatory investigation, birth records for the years 1994–97 from the Hessian Perinatal Survey (HEPS) were accessed to determine whether the incidence of twinning was higher in regions around the TWI compared to adjacent reference areas.

Results: In the environmental study, 61.5% of the children and 95% of their mothers participated. In mothers, twinning was 5.3% in the TWI region compared to 1.6% and 2.3% in the comparison regions. The proportion of mothers with fertility assessment/treatment was 5.7%, 8.3%, and 0% respectively. The prevalence of twinning was not significantly higher (4.5%) in mothers with treatment compared to mothers without (3.7%). From the HEPS, data of 20 603 births was analysed. The incidence of twins was significantly higher in areas which surround the TWI and other industries (1.4–1.6 per 100 births) compared to births in reference areas (0.8 per 100).

Conclusions: Twinning rates may be associated with exposure to industrial pollution. Future environmental health studies that consider multiple births as an outcome are warranted. These should also investigate whether the incidence of monozygotic or dizygotic twinning may be associated with industrial pollution.

  • twin births
  • multiple births
  • incinerator
  • environmental pollution
  • DZ, dizygotic twinning
  • EES, environmental epidemiological study
  • ESIS, European Study on Infertility and Sterility
  • HEPS, Hessian Perinatal Survey
  • MZ, monozygotic twinning
  • OWC, Odenwald control
  • PCA, postal code area
  • RVC, Rhine Valley control
  • TWI, toxic waste incinerator
View Full Text

Statistics from Altmetric.com

Footnotes

  • * The whole area along the River Rhine is meant here, not only the RVC.

  • Financial support: The study was authorised and supported by the former Ministry of Environment, Energy, Youth, Family and Health Hesse, Germany

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Linked Articles

  • Work in brief
    Keith Palmer
  • Education
    M Kundi